260447-16-3Relevant academic research and scientific papers
Efficient syntheses of chiral myo-inositol derivatives-key intermediates in glycosylphosphatidylinositol (GPI) syntheses
Yu, Fei,Guo, Zhongwu
scheme or table, p. 3852 - 3855 (2010/03/02)
A facile and effective method was developed for large-scale syntheses of myo-inositol derivatives with the 1,2,6-O-positions differentiated from each other and from other positions as well. The syntheses started from methyl α-d-glucopyranoside, and the ke
Further probing of the substrate specificities and inhibition of enzymes involved at an early stage of glycosylphosphatidylinositol (GPI) biosynthesis
Crossman Jr., Arthur,Paterson, Michael J.,Ferguson, Michael A.J.,Smith, Terry K.,Brimacombe, John S.
, p. 2049 - 2059 (2007/10/03)
1-D-6-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-1-O-hexadecyl-myo-inositol (14), 1-D-6-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-myo-inositol 1-(octadecyl phosphate) (18), 1-D-6-O-(2-amino-2-deoxy-β-D-glucopyranosyl)-myo-inositol 1-(1,2-di-O-hexadecanoyl-sn-gly
1,2-Diacetals in synthesis: Total synthesis of a glycosylphosphatidylinositol anchor of Trypanosoma brucei
Baeschlin, Daniel K.,Chaperon, Andre R.,Green, Luke G.,Hahn, Michael G.,Ince, Stuart J.,Ley, Steven V.
, p. 172 - 186 (2007/10/03)
A full account on a total synthesis of GPI anchor 1 employing butanediacetal (BDA) groups and a chiral bis(dihydropyran) is presented. The reactivity of selenium and thio glycosides was tuned by the use of BDA groups. This allowed the assembly of an appro
Ready routes to key myo-inositol component of GPIs employing microbial arene oxidation or Ferrier reaction
Jia, Zhaozhong J.,Olsson, Lars,Fraser-Reid, Bert
, p. 631 - 632 (2007/10/03)
Microbial arene oxidation or Ferrier reaction of enol acetates provides versatile complementary routes that greatly facilitate preparation of inositol synthon(s) for GPI assembly.
