64923-60-0

Usage

Chemical Class

Sulfonates

Composition

Butyl group (four carbon atoms), methanesulfonate group (linked through an oxygen atom), and methylsulfonyl group

Usage

Synthetic intermediate in organic chemistry

Applications

Production of pharmaceuticals, agrochemicals, and specialty chemicals

Solubility

High solubility in both organic and aqueous solutions

Industrial Use

Employed as a solvent in various industrial processes

Role

Reagent in the synthesis of organic molecules

Importance

Considered an important building block in the creation of complex chemical structures

Upstream product

• 2612-29-5 2-ethyl-1,3-propandiol 
• 124-63-0 methanesulfonyl chloride 
• 133-13-1 ethyl diethyl malonate 
• 26717-67-9 dimethyl ethylmalonate 

Relevant academic research and scientific papers

SULPHONAMIDES AND COMPOSITIONS THEREOF FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: wherein the variables shown in Formula AA can be as defined anywhere herein. Compounds AA are modulators of NLRP1 and/or NLRP3

CHEMICAL COMPOUNDS AS INHIBITORS OF INTERLEUKIN-1 ACTIVITY

The present disclosure relates to novel sulfonylurea and sulfonyl thiourea compounds and related compounds and their use in treating a disease or condition responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.

Pheromones and analogs from Neozeleboria wasps and the orchids that seduce them: a versatile synthesis of 2,5-dialkylated 1,3-cyclohexanediones

Chiloglottone, a wasp pheromone and attractant of sexually deceptive Chiloglottis orchids, and several structural analogs were synthesized. The synthetic approach is facile, high yielding and versatile, enabling rapid divergence to generate dialkylated analogs of chiloglottone. The key transformation was an organocadmium-mediated desymmetrization of glutaric anhydride derivatives. This library of synthetic 2,5-dialkylated 1,3-cyclohexanediones may assist in future identification of natural products in further species.