261925-40-0

Basic information

• Product Name: Thiophenemethanamine, a-2-thienyl-
• Synonyms: Thiophenemethanamine, a-2-thienyl-;C,C-Di-thiophen-2-yl-methylamine;di(thiophen-2-yl)methanamine;di(2-thiophenyl)methylamine
• CAS NO: 261925-40-0
• Molecular Formula: C₉H₉NS₂
• Molecular Weight: 195.30446
• Mol File: 261925-40-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Thiophenemethanamine, a-2-thienyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophenemethanamine, a-2-thienyl-(261925-40-0)
• EPA Substance Registry System: Thiophenemethanamine, a-2-thienyl-(261925-40-0)

Safety Data

• Hazardous Substances Data: 261925-40-0(Hazardous Substances Data)

Usage

General Description

Thiophenemethanamine, a-2-thienyl- is a chemical compound with the molecular formula C6H7NS. It is a derivative of thiophene and is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also used in the production of polymers and dyes. Thiophenemethanamine, a-2-thienyl- has been studied for its potential antipsychotic and antidepressant properties, as well as its role in the treatment of certain neurological disorders. However, it is important to handle this chemical with caution, as it can be toxic and harmful if not used properly.

Upstream product

• 1003-31-2 thiophene-2-carbonitrile 
• 6973-84-8 2-[α-(2-thienyl)-α-hydroxymethyl]thiophene 
• 10558-44-8 bis(2-thienyl)methanone oxime 
• 1003-09-4 2-bromothiophene 
• 98-03-3 thiophene-2-carbaldehyde 
• 704-38-1 di(thiophen-2-yl)methanone 

Relevant articles and documents

Pd-catalyzed enantioselective C-H iodination: Asymmetric synthesis of chiral diarylmethylamines

An enantioselective C-H iodination reaction using a mono-N-benzoyl- protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.

Synthesis of homo- and heterobiarylmethylamines

A variety of homo- and heterobiarylmethylamines were prepared in modest to high yields via a convenient one-pot process. Georg Thieme Verlag Stuttgart.

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).