26207-59-0

Basic information

• Product Name: 1-(2,4-DIETHOXY-6-HYDROXYPHENYL)ETHANONE
• Synonyms: 1-(2,4-DIETHOXY-6-HYDROXYPHENYL)ETHANONE
• CAS NO: 26207-59-0
• Molecular Formula: C12H16O4
• Molecular Weight: 224.25
• Mol File: 26207-59-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 86–87°C
• Appearance: /
• CAS DataBase Reference: 1-(2,4-DIETHOXY-6-HYDROXYPHENYL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-DIETHOXY-6-HYDROXYPHENYL)ETHANONE(26207-59-0)
• EPA Substance Registry System: 1-(2,4-DIETHOXY-6-HYDROXYPHENYL)ETHANONE(26207-59-0)

Safety Data

• Hazardous Substances Data: 26207-59-0(Hazardous Substances Data)

Usage

Preparation

Obtained from phloroacetophenone triethyl ether by heating with aluminium chloride [.

Upstream product

• 480-66-0 2,4,6-trihydroxyacetophenone 
• 75-03-6 ethyl iodide 
• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 2678-54-8 ketene diethyl acetal 
• 10373-41-8 3,5-diethoxyphenol 
• 75-05-8 acetonitrile 

Relevant articles and documents

Natural product Hirtellanine B and its derivatives in the preparation process for the preparation of medicine for treating tumor with the application of the

The present invention provides a preparation method of a natural product Hirtellanine B, wherein 2,4,6-trihydroxyacetophenone is adopted as a raw material, and steps of compound a preparation, compound b preparation, compound c preparation, compound d preparation, compound e preparation, compound f preparation, compound g preparation, and the like are performed to prepare the natural product Hirtellanine B. According to the present invention, biological activity screening is performed on Hirtellanine B and 14 Hirtellanine B derivatives, and results show that the natural product Hirtellanine B can inhibit proliferations of Jurkat cells, Raji cells and K562 cells, and the compounds provide a certain inhibition activity for tumor cells. The method has characteristics of easily available raw material, high reaction yield and reasonable operation, and is suitable for industrial production. The Hirtellanine B and the derivatives thereof can be used for preparing tumor treatment drugs, and have great clinical values. The natural product Hirtellanine B preparation method reaction formulas are as the follows.