2622-89-1Relevant articles and documents
Abley,Halpern
, p. 1238 (1971)
Boron Schiff bases derived from α-amino acids as nucleoli/cytoplasm cell-staining fluorescent probes: In vitro
Chávez-Reyes, Arturo,Jiménez Pérez, Víctor M.,Lara-Cerón, Jesús A.,Mu?oz-Flores, Blanca M.,Ochoa, María E.,Xochicale-Santana, Leonardo
, p. 31748 - 31757 (2020)
The size, shape, and number of nucleoli in a cell's nucleus might help to distinguish a malignant from a benign tumor. Cellular biology and histopathology often require better visualization to understand nucleoli-related processes, thus organelle-specific fluorescent markers are needed. Here, we report the design, synthesis, and fully chemo-photophysical characterization of fluorescent boron Schiff bases (BOSCHIBAs), derived from α-amino acids (i.e., phenylalanine, tyrosine and tryptophan), with nucleoli- and cytoplasm-specific staining in cells. It is the first time that Boron Schiff bases derived from α-amino acids act as notorious dual (nucleoli and cytoplasm) cell-staining fluorescent probes. The boron derivatives not only showed good photostability and acceptable quantum yields (～5%) in solution, but also exhibited low cytotoxicity (>90% cell viability at 0.1 and 1 μg mL-1), which make them good candidates to be used in medical diagnosis. This journal is
In situ measurements of tetraphenylboron degradation kinetics on clay mineral surfaces by IR
Hunter,Bertsch
, p. 686 - 691 (1994)
An attenuated total reflectance Fourier transform infrared (ATR-IR) spectroscopic method has been developed to quantitatively measure, in situ, the surface-facilitated degradation of tetraphenylboron (TPB) in fully aquated clay pastes. Two pathways for degradation of TPB could be studied both independently and simultaneously. Surface-facilitated oxidation of TPB to diphenylboric acid (DPBA) at Lewis acid sites on clay mineral surfaces was investigated on three members of the smectite family of clays. -from Authors
Structural requirements of 1-(2-pyridinyl)-5-pyrazolones for disproportionation of boronic acids
Bae, Yunsoo,Cho, Joungmo,Han, Yohan,Lee, Hwajeong,Lee, Kee-In,Sadu, Venkata Subbaiah
, (2021/11/27)
We observed an unusual formation of four-coordinate boron(III) complexes from the reaction of 1-(2-pyridinyl)-5-pyrazolone derivatives with arylboronic acids in the basic media. The exact mechanism is not clear; however, the use of unprotected boronic acid and the presence of a bidentate ligand appeared to be the key structural requirements for the transformation. The results suggest that base-promoted disproportionation of arylboronic acid with the assistance of the [N,O]-bidentate ligation of 1-(2-pyridinyl)-5-pyrazolone should take place and facilitate the formation of pyrazole di-arylborinate. Experiments to obtain a deeper understanding of its mechanism are currently underway.
COMPOUNDS AND METHODS FOR THE TREATMENT OF PATHOGENIC NEISSERIA
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Page/Page column 41, (2020/05/06)
Tetracoordinate organoborate compounds, such as compounds harboring a tetraarylborate anion or a triarylalkylborate anion, are shown to exhibit a selective bacteriostatic and bactericidal effect against pathogenic Neisseria species such as N. meningitidis
