26251-91-2Relevant academic research and scientific papers
Selective deoxygenation of leurosine: Concise access to anhydrovinblastine
Hardouin, Christophe,Doris, Eric,Rousseau, Bernard,Mioskowski, Charles
, p. 6571 - 6574 (2007/10/03)
Straightforward access to anhydrovinblastine starting from the parent alkaloid leurosine is reported. The key deoxygenation step was first optimized on a model substrate. However, applied to leurosine, only the low-valent CP2TiCl gave satisfactory results.
Mechanistic Aspects of the Formation of Anhydrovinblasine by Potier-Polonovski Oxidative Coupling of Catharanthine and Vindoline. Spectroscopic Observation and Chemical Reactions of Intermediates
Sundberg, Richard J.,Gadamasetti, Kumar G.,Hunt, Phyllis J.
, p. 277 - 296 (2007/10/02)
The fragmentation-coupling of catharanthine and vindoline by trifluoroacetic anhydride has been carried out under conditions which allow observation of intermediates and comparison of the reactivity by low temperature NMR.These studies have been confirmed
PREPARATION OF 15-OXO-16-METHOXYCARBONYL-15,20-DIHYDRO-CLEAVAMINE AND COUPLING REACTION WITH VINDOLINE
Andriamialisoa, Ratremaniaina Z.,Langlois, Nicole,Langlois, Yves
, p. 245 - 250 (2007/10/02)
Several derivatives of 16-methoxycarbonyl cleavamines oxygenated in position 15 have been prepared and the coupling reaction of 15-oxo 16S-methoxycarbonyl 15,20-dihydro cleavamine with vindoline has been studied.
