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Ethanone, 1-(4-aminophenyl)-2-chloro(9CI), also known as 4’-chloroacetophenone, is a specific organic compound with a molecular formula of C8H7ClNO. It features a benzene ring connected by a carbon atom to a ketone functional group, with an amino (NH2) substituent at the fourth carbon atom of the benzene ring and a chlorine atom on the second carbon atom of the acetone portion. Ethanone, 1-(4-aminophenyl)-2-chloro(9CI) serves as a versatile building block in organic chemistry for synthesizing complex molecules and should be handled with caution due to potential exposure risks.

2631-71-2

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2631-71-2 Usage

Uses

Used in Organic Chemistry:
Ethanone, 1-(4-aminophenyl)-2-chloro(9CI) is used as a building block for synthesizing other complex molecules in the field of organic chemistry. Its unique structure with an amino group and a chlorine atom allows for various chemical reactions and modifications, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethanone, 1-(4-aminophenyl)-2-chloro(9CI) is used as an intermediate in the synthesis of various drugs and drug candidates. Its presence of an amino group enables the formation of amide and urea linkages, which are common in medicinal chemistry for enhancing the biological activity and selectivity of drug molecules.
Used in Agrochemical Industry:
Ethanone, 1-(4-aminophenyl)-2-chloro(9CI) is also utilized in the agrochemical industry as a precursor for the development of pesticides and other crop protection agents. Its structural features can be exploited to create molecules with specific modes of action, contributing to the control of pests and diseases in agriculture.
Used in Chemical Research:
In chemical research, Ethanone, 1-(4-aminophenyl)-2-chloro(9CI) serves as a model compound for studying various reaction mechanisms and exploring new synthetic methodologies. Its reactivity and functional group compatibility make it an ideal candidate for investigating novel transformations and understanding the underlying chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 2631-71-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,3 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2631-71:
(6*2)+(5*6)+(4*3)+(3*1)+(2*7)+(1*1)=72
72 % 10 = 2
So 2631-71-2 is a valid CAS Registry Number.

2631-71-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-Aminophenyl)-2-chloroethanone

1.2 Other means of identification

Product number -
Other names 4-AMINOPHENACYL CHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2631-71-2 SDS

2631-71-2Relevant academic research and scientific papers

Ultrasound promoted clay catalyzed efficient and one pot synthesis of substituted oxindoles

Dandia,Bhati,Jain,Sharma

experimental part, p. 1143 - 1147 (2012/03/10)

A simple facile, one-pot synthesis of oxindoles in reasonable purity is reported via intramolecular Friedal-Craft cyclization. Clay KSF is an inexpensive, efficient and mild catalyst for the synthesis of substituted oxindoles by the reaction of chloroacetyl chloride and various anilines under the influence of ultrasonic irradiation under solvent-free conditions. The remarkable advantages of this method are the simple experimental procedures, short reaction times, high yields of products, suitability for a wide variety of substituents, and the green aspects through the avoidance of toxic catalyst and solvents.

Thiadiazinone derivatives

-

, (2008/06/13)

This invention provides thiadiazinone derivatives represented by the following formula (I) STR1 wherein R1 represents a hydrogen atom or C1 -C5 alkyl, R2 represents a 5- or 6-membered heterocyclic ring having (a) 1-3 nitrogen atoms, (b) a oxygen atom, (c) one sulfur atom, (d) 1-3 nitrogen atoms and one oxygen atom, or (e) 1-3 nitrogen atoms and one sulfur atom each of which rings may optionally be substituted by at least one substituent selected from the group consisting of C1 -C5 alkyl, cyano, hydroxy, C1 -C5 alkoxy, amino, C1 -C5 alkylamino, C2 -C6 dialkylamino, C2 -C5 acylamino, carboxyl, C2 -C5 alkoxycarbonyl and carbamoyl; or a pharmaceutically acceptable salt thereof. The compounds according to the present invention have an excellent cardiotonic activity, and are useful as active ingredients of a cardiotonic drug.

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