263746-53-8

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 106-53-6 para-bromobenzenethiol 
• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 5335-84-2 bis(4-bromophenyl)disulfide 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 51172-60-2 ethyl (4-chlorobenzyl)carbamate 
• 35573-36-5 N-(4-methoxyphenylmethyl)carbamic acid ethyl ester 
• 2621-78-5 ethyl N-benzylcarbamate 
• 444901-21-7 ethyl 3-chlorobenzylcarbamate 
• 17101-98-3 (4-methyl-benzyl)carbamic acid ethyl ester 

Relevant academic research and scientific papers

A new method for synthesis of S-aryl-O-alkyl thiolcarbonates: Selenium-catalyzed reaction of alcohols with carbon monoxide and diaryl disulfides

A unique catalytic ability of selenium has been developed. When alcohols were allowed to react with diaryl disulfides in the presence of a catalytic amount of selenium under a pressurized carbon monoxide, S-aryl-O-alkyl thiolcarbonates were obtained in moderate to good yields.

Convenient route to thiocarbonates from alcohols, thiols, and triphosgene

An efficient and simple one-pot, three-component procedure has been introduced for the preparation of various thiocarbonates from thiols, alcohols, and triphosgene in dichloromethane. Copyright Taylor & Francis Group, LLC.

Kinetics and mechanism of the aminolysis of O-ethyl S-aryl thiocarbonates in acetonitrile

The Kinetics and mechanism of the reactions of O-ethyl S-(Z)aryl thiocarbonates with (X)benzylamines in acetonitrile at 45.0 °C are studied. Relatively small values of βx (βnuc) = 0.6 to approximately 0.8 and βz (βlg) = -0.5 to approximately -0.7 together with a negative cross-interaction constant ρxz (= -0.47) and failure of the reactivity-selectivity principle (RSP) are interpreted to indicate a concerted mechanism. The normal kinetic isotope effects (kH/kD = 1.3 to approximately 1.8) involving deuterated benzylamine nucleophiles suggest a hydrogen-bonded, four-center-type transition state.