51172-60-2

Basic information

• Product Name: ethyl (4-chlorobenzyl)carbamate
• Synonyms: ethyl (4-chlorobenzyl)carbamate
• CAS NO: 51172-60-2
• Molecular Weight: 213.664
• Mol File: 51172-60-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl (4-chlorobenzyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (4-chlorobenzyl)carbamate(51172-60-2)
• EPA Substance Registry System: ethyl (4-chlorobenzyl)carbamate(51172-60-2)

Safety Data

• Hazardous Substances Data: 51172-60-2(Hazardous Substances Data)

Upstream product

• 78725-90-3 S-phenyl-O-ethyl thiolcarbonate 
• 104-86-9 4-chlorobenzylamine 
• 107701-35-9 O-ethyl S-(4-chlorophenyl) thiocarbonate 
• 78725-88-9 O-ethyl S-(4-methylphenyl) thiocarbonate 
• 263746-53-8 O-ethyl-S-(4-bromophenyl)thiocarbonate 
• 64-17-5 ethanol 
• 6951-40-2 2-((4-chlorobenzyl)amino)-2-oxoacetic acid 
• 124-38-9 carbon dioxide 
• 1878-66-6 4-chlorophenylacetic Acid 
• 57676-51-4 2-(4-chlorophenyl)acetic hydrazide 
• 14062-24-9 4-chloro-benzeneacetic acid, ethyl ester 
• 22719-89-7 ethyl m-nitrophenyl carbonate 
• 22719-86-4 1-(4-ethoxycarbonyloxy-phenyl)-ethanone 
• 6132-45-2 ethyl 4-nitrophenyl carbonate 

Downstream Products

• 444901-25-1 ethyl 4-chlorobenzyl[2,4-dinitro-6-(trifluoromethyl)phenyl]carbamate 
• 51172-62-4 N-(p-Chlorbenzyl)-N-(α-cyano-β-aethoxyacryloyl)-carbaminsaeureaethylester 
• 51172-61-3 N-p-Chlorbenzyl-N-cyanoacetylcarbaminsaeureaethylester 
• 42365-43-5 (4-chlorophenyl)methanamine hydrochloride 

Relevant articles and documents

Urethanes synthesis from oxamic acids under electrochemical conditions

Urethane synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in situ generation of isocyanates by anodic oxidation of oxamic acids in an alcoholic medium. The reaction is applicable to a wide range of oxamic acids, including chiral ones, and alcohols furnishing the desired urethanes in a one-pot process without the use of a chemical oxidant.

An efficient one-pot synthesis of: N, N ′-disubstituted ureas and carbamates from N -acylbenzotriazoles

A facile and high-yielding one-pot synthesis of carbamates and N,N′-disubstituted symmetrical ureas from N-acylbenzotriazoles has been devised. It is believed that, the intermediate acyl-azide undergo Curtius rearrangement and in different solvents gives different products i.e. carbamates in alcohols and N,N′-disubstituted symmetrical urea in THF.

Kinetics and mechanism of the aminolysis of O-ethyl S-aryl thiocarbonates in acetonitrile

The Kinetics and mechanism of the reactions of O-ethyl S-(Z)aryl thiocarbonates with (X)benzylamines in acetonitrile at 45.0 °C are studied. Relatively small values of βx (βnuc) = 0.6 to approximately 0.8 and βz (βlg) = -0.5 to approximately -0.7 together with a negative cross-interaction constant ρxz (= -0.47) and failure of the reactivity-selectivity principle (RSP) are interpreted to indicate a concerted mechanism. The normal kinetic isotope effects (kH/kD = 1.3 to approximately 1.8) involving deuterated benzylamine nucleophiles suggest a hydrogen-bonded, four-center-type transition state.