5335-84-2

Usage

Uses

Used in Rubber Industry:
BIS(4-BROMOPHENYL)DISULFIDE is used as a rubber chemical additive to enhance the mechanical properties and resistance to heat, oxidation, and flex cracking. Its incorporation into rubber formulations improves the overall performance and durability of rubber products.
Used in Polymer Chemistry:
In the field of polymer chemistry, BIS(4-BROMOPHENYL)DISULFIDE serves as a cross-linking agent, particularly in the production of thermosetting plastics and rubbers. It helps in creating a three-dimensional network structure, which imparts rigidity and stability to the final product.
Used in Pharmaceutical and Agrochemical Synthesis:
BIS(4-BROMOPHENYL)DISULFIDE can be used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique chemical structure allows for the development of new compounds with potential therapeutic or pesticidal properties.
Safety Precautions:
Although BIS(4-BROMOPHENYL)DISULFIDE is considered to have low toxicity, it is essential to handle it with care. Inhalation or ingestion should be avoided, and appropriate protective equipment, such as gloves and goggles, should be used to prevent skin and eye irritation during handling and processing.

Upstream product

• 3226-41-3 4-bromobenzenediazonium tetrafluoroborate 
• 512-35-6 benzenesulfonic anhydride 
• 108-98-5 thiophenol 
• 106-53-6 para-bromobenzenethiol 
• 882-33-7 diphenyldisulfane 
• 106-40-1 4-bromo-aniline 
• 104-95-0 (4-bromophenyl)thioanisole 
• 40897-58-3 1-(4-bromophenyl)-2-(4-nitrophenyl)disulfane 
• 20057-86-7 bis(p-bromophenyl) trisulfide 
• 141425-74-3 4-bromophenyl 4-methylphenyl disulphone 
• 72708-54-4 Lithium 4-bromobenzenesulfinate 
• 201230-82-2 carbon monoxide 
• 622-29-7 N-Benzylidenemethylamine 
• 18620-02-5 (4-bromophenyl)magnesium bromide 

Downstream Products

• 101894-61-5 bis-benzenesulfonyl-(4-bromo-phenylsulfanyl)-methane 
• 106-53-6 para-bromobenzenethiol 
• 100329-64-4 C₁₂H₉BrClNO₂S₂ 
• 113525-41-0 2-S-(p-bromophenyl)dibenzothiophene 
• 150192-63-5 4-(4-Bromphenylthio)-4'-methyldiphenylsulfid 
• 31053-90-4 C₆H₄BrS 
• 3347-03-3 S-4-bromophenyl 4-bromobenzenesulfonothioate 
• 32338-03-7 S-(4-Bromo-phenyl)-N-phenyl-thiohydroxylamine 
• 40939-34-2 diethyl 2-((4-bromophenyl)thio)malonate 
• 16411-18-0 vinyl-4'-bromophenyl sulfide 
• 782491-17-2 1-bromo-4-[(pentafluoroethyl)thio]-benzene 
• 6334-55-0 allyl (4-bromophenyl)sulfide 
• 263746-53-8 O-ethyl-S-(4-bromophenyl)thiocarbonate 
• 65662-88-6 phenyl(4-bromophenyl)sulfide 

Relevant academic research and scientific papers

Mn(III) complex supported on Fe 3O 4 nanoparticles: Magnetically separable nanocatalyst for selective oxidation of thiols to disulfides

A manganese(III) complex, [Mn(phox)2(CH3OH) 2]ClO4 (phox = 2-(2′-hydroxyphenyl)oxazoline), was immobilized on silica-coated magnetic Fe3O4 nanoparticles through the amino propyl linkage usi

Transformation of arylboronic acids with sodium thiosulfate into organodisulfides catalyzed by a recyclable polyoxometalate-based Cr(iii) catalyst

Organo disulfides represent an abundant class of compounds in chemical biology, pharmaceutical fields, and industry. They are traditionally synthesized by the oxidation of mercaptan in the presence of an organic ligand supported metal catalyst or toxic oxidants under harsh conditions. Here, we disclose a highly-efficient pathway in which disulfide is synthesized by organic boric acid and Na2S2O3 using the catalyst (NH4)3[CrMo6O18(OH)6], demonstrating a high activity and excellent selectivity. Various boric acid derivatives have been successfully transformed into the corresponding disulfides. Mechanistic insights have been furnished based on the observation of intermediate and control experiments.

Oxo-vanadium(IV) unsymmetrical Schiff base complex immobilized on γ-Fe2O3 nanoparticles: A novel and magnetically recoverable nanocatalyst for selective oxidation of sulfides and oxidative coupling of thiols

In this research, an unsymmetrical salen-type oxo-vanadium(IV) complex, [VO(salenac-OH)] (salenac-OH = [9-(2′,4′-dihydroxyphenyl)-5,8-diaza-4-methylnona-2,4,8-trienato](-2)), was synthesized and covalently immobilized on the surface of magnetic γ-Fe2

Copper based on diaminonaphthalene-coated magnetic nanoparticles as robust catalysts for catalytic oxidation reactions and C-S cross-coupling reactions

In this work, the immobilization of copper(ii) on the surface of 1,8-diaminonaphthalene (DAN)-coated magnetic nanoparticles provides a highly active catalyst for the oxidation reaction of sulfides to sulfoxides and the oxidative coupling of thiols to disulfides using hydrogen peroxide (H2O2). This catalyst was also applied for the one-pot synthesis of symmetrical sulfidesviathe reaction of aryl halides with thiourea as the sulfur source in the presence of NaOH instead of former strongly basic and harsh reaction conditions. Under optimum conditions, the synthesis yields of sulfoxides, symmetrical sulfides, and disulfides were about 99%, 95%, and 96% respectively with highest selectivity. The heterogeneous copper-based catalyst has advantages such as the easy recyclability of the catalyst, the easy separation of the product and the less wastage of products during the separation of the catalyst. This heterogeneous nanocatalyst was characterized by FESEM, FT-IR, VSM, XRD, EDX, ICP and TGA. Furthermore, the recycled catalyst can be reused for several runs and is economically effective.

Preparation method of symmetric disulfide bond-containing compound

The method comprises the following steps: adding a raw material and an oxidant to a reaction bottle containing a solvent; reacting 23W - 85W under the irradiation of 12 - 24h energy-saving lamps; and purifying the reaction product to obtain symmetrical disulfide bond-containing compounds. The raw material is mercaptan or thiophenol. The oxidizing agent is trichlorobromomethane, and the solvent is tetrahydrofuran. The method has the advantages of simple operation, high yield (70 - 90%), wide applicability, cheap and easily available raw materials, and provides a better way for the synthesis and production of symmetrical disulfide bond-containing compounds.

Direct NO Reduction by a Biomimetic Iron(II) Pyrazolate MOF

A novel metal-organic framework (MOF) containing one-dimensional, Fe2+ chains bridged by dipyrazolate linkers and N,N-dimethylformamide (DMF) ligands has been synthesized. The unusual chain-type metal nodes feature accessible coordination sites on adjacent metal centers, resulting in motifs that are reminiscent of the active sites in non-heme diiron enzymes. The MOF facilitates direct reduction of nitric oxide (NO), producing nearly quantitative yields of nitrous oxide (N2O) and emulating the reactivity of flavodiiron nitric oxide reductases (FNORs). The ferrous form of the MOF can be regenerated via a synthetic cycle involving reduction with cobaltocene (CoCp2) followed by reaction with trimethylsilyl triflate (TMSOTf).

Visible-light photocatalytic selective aerobic oxidation of thiols to disulfides on anatase TiO2

This work presents the visible-light photocatalytic selective oxidation of thiols to disulfides with molecular oxygen (O2) on anatase TiO2. The high specific surface area of anatase TiO2 proved to be especially critical in

TEMPO visible light photocatalysis: The selective aerobic oxidation of thiols to disulfides

TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) is well-established in orangocatalysis that usually work in synergy with transition-metal catalysis or semiconductor photocatalysis. Here, TEMPO was turned into a visible light photocatalyst to conduct the selective aerobic oxidation of thiols into disulfides. With O2 as an oxidant, a mild and efficient protocol for the selective oxidation of thiols into disulfides including symmetrical and unsymmetrical ones with 5 molpercent of TEPMO as a photocatalyst was developed at room temperature under the irradiation of 460 nm blue LEDs. It was found that a complex formed between TEMPO and thiols underpinned the visible light activity and disulfides were obtained in very high isolated yields. This work suggests that TEMPO takes diverse roles in for photocatalytic selective oxidative transformations with O2 as the oxidant.

Synthesis and characterization of VO–vanillin complex immobilized on MCM-41 and its facile catalytic application in the sulfoxidation reaction, and synthesis of 2,3-dihydroquinazolin-4(1H)-ones and disulfides in green media

In this work, a vanillin complex is immobilized onto MCM-41 and characterized by FT-IR, X-ray diffraction, scanning electron microscopy, energy dispersive spectroscopy, thermogravimetric analysis, and BET techniques. This supported Schiff base complex was found to be an efficient and recoverable catalyst for the chemoselective oxidation of sulfides into sulfoxides and thiols into their corresponding disulfides (using hydrogen peroxide as a green oxidant) and also a suitable catalyst for the preparation of 2,3-dihydroquinazolin-4(1H)-one derivatives in water at 90°C. Using this protocol, we show that a variety of disulfides, sulfoxides, and 2,3-dihydroquinazolin-4(1H)-one derivatives can be synthesized in green conditions. The catalyst can be recovered and recycled for further reactions without appreciable loss of catalytic performance.

Fe3O4@MCM-41@Zn-Arg: as a novel, magnetically recoverable and ecofriendly nanocatalyst for the synthesis of disulfides, sulfoxides and 2,3-dihydroquinazolin?4(1H)?ones

The direct supporting of Zn-arginine complex on magnetic core-shell nanostructures (Fe3O4@MCM-41@Zn-Arg) was reported as a novel, heterogeneous and excellent nanocatalyst, which applied for the oxidation reaction of sulfides to sulfoxides, oxidative coupling of thiols to their corresponding disulfides and the synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives under mild conditions. The structure of the catalyst was studied by X-Ray diffraction, Fourier transform-infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy, atomic absorption spectroscopy, and vibrating sample magnetometry techniques. The simple experimental procedure, very good catalytic activity, low cost, and excellent recycling are the noteworthy features of the currently employed heterogeneous catalytic system.