264255-44-9Relevant academic research and scientific papers
Diastereoselective synthesis of 2-aryl-3-aminoazepanes via a novel ring- enlargement process
Cutri, Sabrina,Bonin, Martine,Micouin, Laurent,Froelich, Olivier,Quirion, Jean-Charles,Husson, Henri-Philippe
, p. 1179 - 1182 (2000)
Syntheses of optically pure 2-aryl-3-aminoazepanes derived from 2-cyano 6-oxazolopiperidine are described. The key step involves a one-pot reduction and ring-enlargement process occurring in a highly regio- and stereoselective way. (C) 2000 Elsevier Scien
Practical asymmetric synthesis of 1,2-diamines in the 3-aminoazepane series
Cutri,Bonin,Micouin,Husson,Chiaroni
, p. 2645 - 2651 (2007/10/03)
A simple and versatile method for the enantio- and diastereoselective synthesis of mono- or disubstituted 3-aminoazepanes is described. The key step involves a highly regio- and diastereoselective tandem ring-enlargement/alkylation or reduction process. T
