2650-51-3Relevant academic research and scientific papers
A mitochondria-targeting supramolecular photosensitizer based on pillar[5]arene for photodynamic therapy
Rui, Leilei,Xue, Yudong,Wang, Yong,Gao, Yun,Zhang, Weian
, p. 3126 - 3129 (2017)
A mitochondria-targeting supramolecular photosensitizer system TPP-QAS/WP5/DTAB was constructed based on a host-guest inclusion complex. The supramolecular system could efficiently release and activate TPP-QASs in an acidic environment, which have been demonstrated to preferentially accumulate in mitochondria. Singlet oxygen (1O2) could be in situ generated in mitochondria under light irradiation, further enhancing the PDT efficacy.
PH-Responsive supramolecular vesicles assembled by water-soluble pillar[5]arene and a BODIPY photosensitizer for chemo-photodynamic dual therapy
Meng, Lu-Bo,Zhang, Wenyi,Li, Dongqi,Li, Yan,Hu, Xiao-Yu,Wang, Leyong,Li, Guigen
supporting information, p. 14381 - 14384 (2015/09/21)
Supramolecular vesicles which can successfully encapsulate DOX and exhibit rapid drug release in a low-pH environment are constructed based on the host-guest interaction of water-soluble pillar[5]arene and a BODIPY derivative. They show remarkable combina
Odd-even effect and unusual behavior of dodecyl-substituted analogue observed in the crystal structure of alkyltrimethylammonium-[Ni(dmit) 2]- salts
Dai, Kotaro,Nomoto, Kuniharu,Ueno, Shinji,Tomono, Kazuaki,Miyamura, Kazuo
experimental part, p. 312 - 319 (2011/05/13)
A series of [Ni(dmit)2]- (dmit: 1,3-dithiole-2- thione-4,5-dithiolato) salts of alkyltrimethylammonium (Cn: n represents the alkyl chain length; n = 3 and 518) have been prepared and analyzed by X-ray structural analysis. All complex salts have been found to be composed of alternate sheets of [Ni(dmit)2]- anions and sheets of cations with a pronounced interdigitation of the alkyl chains. However, molecular arrangement differed between (C3)[Ni(dmit)2] and other (Cn)[Ni(dmit)2] (n = 518). Adjacent cations were aligned along the long axis of [Ni(dmit)2]- anion in C3 complex salt, while in others (C5-C18 complex salts), they were aligned toward the short axis. Such a difference in arrangement arose from correlativity between the lengths of the long axis of cation and anion, namely CLCA. Furthermore, relative orientation between the alkyl chain of cation and [Ni(dmit)2]- anion differed between the odd- and even-numbered cations for C10-C18. Whereas the plane of alkyl chain for odd-numbered cation was normal to the plane of [Ni(dmit)2]- anion, that of even-numbered cation was parallel. It was also found that C12 analog behaved like odd-numbered cations. However, in C12 salt, the end methyl group of the dodecyl group adopted unusual end-gauche conformation.
A Proton NMR Study on the Structure of Water of Hydration of Aqueous Micelles
El Seoud, Monica I.,Farah, Joao P. S.,El Seoud, Omar A.
, p. 180 - 183 (2007/10/02)
The chemical shift of water was measured as a function of concentration of the detergents cetyltrimethylammonium chloride, CTACl; 3-N-dodecyl-N,N-dimethylammonio-1-propanesulfonate, DDAPS; polyoxyethylene (9.5) octylphenyl ether, Triton X-100, and the deuterium content of the solvent.The short chain compound butyltrimethylammonium bromide was also studied as a model for CTACl.Graphs of the chemical shifts vs. the mole fractions of the solubilizates were linear in all cases and the slopes were used to calculate the so called "fractionation factor, φ" which can be used as a measure of the degree of structure of the water of hydration of the appropriate species (relative to bulk water).The calculated φ values indicated that the butyltrimethylammonium ion does not perturb hydrogen bonding of the solvent (φ = 0.99), whereas the water in the Stern layer of CTACl is more organized than bulk water (φ = 1.06).Zwitterionic DDAPS was found to enhance the structuring marginally (φ = 1.02) whereas the nonionic surfactant Triton X-100 has a structure decreasing effect (φ = 0.95). - Keywords: Colloides / H/D Fractionation / Isotope Effects / Micelles / Spectroscopy, Nuclear Magnetic Resonance
Volumes and heat capacities of transfer of ammonium salts from water to aqueous octyldimethylamine oxide at 25 deg C
Hetu, Daniel,Desnoyers, Jacques E.
, p. 767 - 773 (2007/10/02)
The effect of an additive on a water-surfactant system can be studied through thermodynamic functions of transfer of the additive from water to aqueous solutions of the surfactant.These thermodynamic functions often go through extrema in the region of the critical micellar concentration (cmc) of the surfactant.As it can be shown with a simple chemical equilibrium model, the general shape of the transfer functions is primarily related to the pair-wise hydrophobic interactions between the additive and the surfactant monomers, to a shift in the monomer-micelle equilibrium and to the distribution of the additive between the aqueous phase and the micelles.Medium and electrostatic effects are also possible, especially with ionic systems.To separate these effects and identify the salts which distribute themselves in the micelles, the volumes and heat capacities of transfer of hydrophobic ammonium salts from water to aqueous solutions of dimethyloctylamine oxide have been investigated.The short chain salts have only a small effect on monomer-micelle equilibrium by salting out the monomers, whereas the more hydrophobic ones participate also to the micellization process, shifting more strongly the surfactant monomer-micelle equilibrium.
