26537-68-8

Basic information

• Product Name: 1-benzofuran-3-carboxylic acid
• Synonyms: 1-benzofuran-3-carboxylic acid;3-Benzofurancarboxylic acid;Benzo[b]furan-3-carboxylic acid 97%;1-benzofuran-3-carboxylic acid(SALTDATA: FREE);3-Carboxybenzo[b]furan;3-Carboxybenzo[b]furan, 1-Benzofuran-3-carboxylic acid;Benzo[b]furan-3-carboxylicacid97%;Benzo[b]furan-3-carboxylic acid
• CAS NO: 26537-68-8
• Molecular Formula: C₉H₆O₃
• Molecular Weight: 162.15
• EINECS: 200-258-5
• Mol File: 26537-68-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 162℃
• Boiling Point: 325.6°Cat760mmHg
• Flash Point: 150.7°C
• Appearance: /
• Density: 1.363g/cm³
• Vapor Pressure: 9.31E-05mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.19±0.10(Predicted)
• CAS DataBase Reference: 1-benzofuran-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzofuran-3-carboxylic acid(26537-68-8)
• EPA Substance Registry System: 1-benzofuran-3-carboxylic acid(26537-68-8)

Safety Data

• Hazardous Substances Data: 26537-68-8(Hazardous Substances Data)

Usage

General Description

1-Benzofuran-3-carboxylic acid is a chemical compound with the molecular formula C9H6O3. It is a derivative of benzofuran and has a carboxylic acid group attached to the third position of the benzene ring. 1-benzofuran-3-carboxylic acid is commonly used in the pharmaceutical industry as a building block for the synthesis of various bioactive molecules and pharmaceutical drugs. It has been studied for its potential anti-tumor, antioxidant, and anti-inflammatory properties. Additionally, 1-benzofuran-3-carboxylic acid has also been investigated for its role in the development of new therapies for neurological disorders.

InChI:InChI=1/C9H6O3/c10-9(11)7-5-12-8-4-2-1-3-6(7)8/h1-5H,(H,10,11)

Upstream product

• 131-76-0 1-benzofuran-2,3-dicarboxylic acid 
• 91-22-5 quinoline 
• 59214-70-9 3-bromobenzofuran 
• 60-29-7 diethyl ether 
• 4687-24-5 benzofuran-3-carboxylic acid methyl ester 
• 124-38-9 carbon dioxide 
• 40800-90-6 3-(α-methoxy)methylene benzofuran-2-(3H)-ketone 
• 859979-88-7 (2-methoxycarbonylmethoxy-phenyl)-glyoxylic acid methyl ester 
• 93334-77-1 (2-carboxymethoxy-phenyl)-glyoxylic acid 
• 4732-72-3 coumarandione 
• 129-92-0 3-ethoxycarbonylbenzofuran-2-carboxylic acid 
• 194278-43-8 benzofuran-3-carboxylic acid ethyl ester 
• 4687-25-6 1-benzofuran-3-carbaldehyde 
• 109-72-8 n-butyllithium 

Downstream Products

• 271-89-6 1-benzofurane 
• 111964-21-7 benzo[b]furan-3-carbonyl chloride 
• 119-84-6 C₆H₄(CH₂CH₂C(O)O) 
• 39891-55-9 2,3-dihydrobenzo[b]furan-3-carboxylic acid 
• 959304-51-9 benzofuran-3-carboxamide 
• 82156-58-9 benzofuran-3-yl-acetic acid ethyl ester 
• 64175-51-5 2-(3-benzofuranyl)acetic acid 
• 82156-38-5 C₁₇H₁₅NO₄S 
• 103981-42-6 <2-(trideuteriomethyl)-3-benzofuryl>methyl benzoate 
• 98115-19-6 (2-methyl-3-benzofuryl)methyl benzoate 
• 28222-80-2 3-(4-methoxybenzoyl)benzofuran 
• 4687-25-6 1-benzofuran-3-carbaldehyde 
• 4687-23-4 3-hydroxymethylbenzofuran 
• 3265-74-5 2-methyl-1-benzofuran-3-carboxylic acid 

Relevant articles and documents

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A benzofuran -3 - carboxylic acid (by machine translation)

The invention relates to a benzofuran - 3 - carboxylic acid preparation method, the method using the intermediate 1 as raw materials, under alkaline conditions in the open-loop, the closed-loop process for preparing benzofuran - 3 - carboxylic acid. The method is characterized in that the mild reaction conditions, the operation is simple, high yield, is suitable for industrial production. (by machine translation)

ANTI-HIV COMPOUNDS

Thiazole derivatives represented by Formula (I) are disclosed, where R1, R2, R3, A, X, Y, Z, R6 and R7 are disclosed herein. These thiazole derivatives and pharmaceutical compositions comprising these derivatives are useful in the treatment of HIV mediated diseases and conditions.

NOVEL INDOL CARBOXYLIC ACID BISPYRIDYL CARBOXAMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD AND COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT

Disclosed herein are a new indole carboxylic acid bispyridyl carboxamide derivative, a preparation method thereof, and a composition for prevention or treatment of obesity, urinary disorders, and CNS disorders, containing the same as an active ingredient. Because the indole carboxylic acid bispyridyl carboxamide derivatives according to the present invention have high affinity for 5-HT2c receptors, act selectively on the 5-HT2c receptors, the derivatives rarely have adverse effects caused by other receptors. Because the derivatives effectively inhibit serotonin activity, they may be useful for treatment or prevention of obesity; urinary disorders such as urinary incontinence, premature ejaculation, erectile dysfunction, and prostatic hyperplasia; CNS disorders such as depression, anxiety, concern, panic disorder, epilepsy, obsessive-compulsive disorder, migraine, sleep disorder, withdrawal from drug abuse, Alzheimer's disease, and schizophrenia, associated with 5-HT2c receptors.