2658-92-6Relevant academic research and scientific papers
Stereocontrol in a combined allylic azide rearrangement and intramolecular schmidt reaction
Liu, Ruzhang,Gutierrez, Osvaldo,Tantillo, Dean J.,Aube, Jeffrey
, p. 6528 - 6531 (2012/06/15)
Pre-equilibration of an interconverting set of isomeric allylic azides is coupled with an intramolecular Schmidt reaction to afford substituted lactams stereoselectively. The effect of substitution and a preliminary mechanistic study are reported. The syn
An efficient one-pot four-step domino reaction for the synthesis of C2-substituted 3-methylcyclohex-2-enones
Goncalves, Sylvie,Maillos, Philippe,Nicolas, Marc,Wagner, Alain,Baati, Rachid
experimental part, p. 7856 - 7860 (2010/11/18)
An efficient one-pot four-step domino reaction of substituted β-ketoesters has been optimized giving rise to a large panel of C2-substituted 3-methylcyclohex-2-enones, an important scaffold for the preparation of various initiators for cationic or radical cyclizations. The developed methodology is quite general and applicable to a wide range of β-ketoester substrates, allowing the introduction of various functionalities at the C2 position of the 3-methylcyclohex-2-enones, in good to excellent yields.
Stereospecific total synthesis of amberketal and a homologue
Kongkathip, Boonsong,Kongkathip, Ngampong,Janthorn, Sirinan,Virarangsiyakorn, Duangmanee
, p. 51 - 52 (2007/10/03)
Amberketal (1a) and acetal homologue (2a) have been synthesised from a commercially available methyl acetoacetate involving palladium catalysed cyclisation as a key step.
THE INFLUENCE OF HYDROGEN BONDING ON THE SOLVOLYTIC REACTIVITY OF NICOTINATES IN FLUORINATED ALCOHOLS
Jursic, Branko,Sunko, Dionis E.,Ladika, Mladen
, p. 4367 - 4376 (2007/10/02)
A systematic investigation of solvolytic reactivities of allylic and benzylic nicotinates and their N-methylated derivatives in 80percent EtOH, 97percent TFE and 97percent HFIP was undertaken.The nicotinates in 97percent HFIP are slightly more reactive th
Solvolysis of 2-Alkenyl-2-cyclohexenyl p-Nitrobenzoates
Ladika, Mladen,Sunko, Dionis E.
, p. 4544 - 4548 (2007/10/02)
In an attempt to study possible ?-participation in allyl derivatives, 2-alkenyl-3-methyl-2-cyclohexenyl p-nitrobenzoates 6 and 7 were solvolyzed in 97 wt percent trifluoroethanol and 80 vol percent ethanol.These esters show in both solvents a solvolysis r
3-Methylcyclohex-2-enone Derivatives as Initiators of Cyclisation. Part 1. Introduction and Synthesis of 2-Substituted 3-methylcyclohex-2-enones
Amupitan, Joseph A.,Huq, Enamul,Mellor, Michael,Scovell, Edward G.,Sutherland, James K.
, p. 747 - 749 (2007/10/02)
A series of C-2 substituted 3-methylcyclohex-2-enones has been prepared using the Hagemann ester route.A new synthesis of these compounds has been developed which involves the alkylation of the N,N-diethylaminoethyl ether of 1-hydroxy-5-methylcyclohexa-1,5-diene.The cyclohexenones have been converted into the corresponding α,β-epoxyketones using alkaline hydrogen peroxide.
CYCLIZATION OF 1,3-DISUBSTITUTED 2-(3-BUTENYL)-2-CYCLOHEXEN-1-OLS
Brunke, E.-J.,Hammerschmidt, F.-J.,Struwe, H.
, p. 1033 - 1038 (2007/10/02)
The cationic cyclization cyclohexanols 8a-c gave mixtures of the octalinols 9a-c and 10a-c with 9a-c as a main products.By cyclization of the isomeric educts 13a-c, the same products were formed in different proportions.
ACID CATALYZED COPE REARRANGEMENTS OF 2-ACYL-1,5-DIENES
Dauben, William G.,Chollet, Andre
, p. 1583 - 1586 (2007/10/02)
The Cope rearrangement of 1,5-dienes bearing acyl substitutents in the 2-position of the diene system is strongly accelerated by protic and Lewis acids.
