266369-69-1

Basic information

• Product Name: Carbamic acid, [(1R)-1-(3-hydroxyphenyl)ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 266369-69-1
• Molecular Formula: C13H19NO3
• Molecular Weight: 237.299
• Mol File: 266369-69-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1R)-1-(3-hydroxyphenyl)ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1R)-1-(3-hydroxyphenyl)ethyl]-, 1,1-dimethylethyl ester(266369-69-1)
• EPA Substance Registry System: Carbamic acid, [(1R)-1-(3-hydroxyphenyl)ethyl]-, 1,1-dimethylethyl ester(266369-69-1)

Safety Data

• Hazardous Substances Data: 266369-69-1(Hazardous Substances Data)

Upstream product

• 121-71-1 3-Hydroxyacetophenone 
• 1372628-56-2 3-((R)-1-((R)-1-phenylethylamino)ethyl)phenol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 88196-70-7 (R)-1-(3-methoxyphenyl)ethylamine 
• 518060-42-9 (R)-1-(3-hydroxyphenyl)ethylamine 
• 871728-33-5 (R)-[1-(3-methoxyphenyl)ethyl]carbamic acid tert-butyl ester 

Downstream Products

• 871728-33-5 (R)-[1-(3-methoxyphenyl)ethyl]carbamic acid tert-butyl ester 
• 1006592-90-0 3-(2-chlorophenyl)-N-[(R)-1-(3-methoxyphenyl)ethyl]-2-propenamide 
• 1167414-89-2 (R)-1-(3-methoxyphenyl)ethanamine hydrochloride salt 
• 148717-49-1 tecalcet 
• 177172-48-4 (R)-3-(2-chlorophenyl)-N-(1-(3'-methoxyphenyl)ethyl)propanamide 
• 943153-36-4 (R)-[1-(3-hydroxy-4-iodo-phenyl)-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

RHO KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF

Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.

SUBSTITUTED BENZOTRIAZINES AND QUINOXALINES AS INHIBITORS OF P7OS6 KINASE

The invention provides compounds of the formula (1): or salts or tautomers thereof; wherein X1 is N or N+(O ); X2 is N or CH; Q is a C1-3 alkylene group; R1 is selected from hydrogen, C1-4 hydrocarbyl and hydroxy-C2-4 hydrocarbyl; R2, R3 and R4 are the same or different and each is selected from hydrogen, fluorine, chlorine and methyl; Ar1 is an optionally substituted monocyclic 5 or 6-membered aryl or heteroaryl ring containing 0, 1 or 2 heteroatom ring members selected from O, N and S, or a naphthyl ring and Ar2 is an optionally substituted monocyclic 5 or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S. The compounds of formula (1) are inhibitors of p70S6 kinase and are useful in the treatment of proliferative diseases.

AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME

Compounds of a formula: wherein Ring A represents an optionally-substituted aromatic ring; Ring B represents an optionally-substituted cyclic hydrocarbon group; Z represents an optionally-substituted cyclic group; R1 represents a hydrogen atom, an optionally-substituted hydrocarbon group, an optionally-substituted heterocyclic group, or an acyl group; R2 represents an optionally-substituted amino group; D represents a chemical bond or a divalent group; E represents -CO-, -CON(Ra)-, COO-, -N(Ra)CON(Rb)-, -N(Ra)COO-, -N(Ra)SO2-, -N(Ra)-, -O-, -S-,-SO- or -SO2- (in which Ra and Rb each independently represent a hydrogen atom or an optionally-substituted hydrocarbon group); G represents a chemical bond or a divalent group; L represents (1) a chemical bond or (2) a divalent hydrocarbon group optionally having from 1 to 5 substituents selected from;(i) a C1-6 alkyl group,(ii) a halogeno-C1-6 alkyl group,(iii) a phenyl group,(iv) a benzyl group,(v) an optionally-substituted amino group,(vi) an optionally-substituted hydroxy group, and(vii) a carbamoyl or thiocarbamoyl group optionally substituted by: a C1-6 alkyl group, an optionally-substituted phenyl group, or an optionally-substituted heterocyclic group, and optionally interrupted by -O- or -S-; X represents an oxygen atom, an optionally-oxidized sulfur atom, an optionally-substituted nitrogen atom, or an optionally-substituted divalent hydrocarbon group; Y represents two hydrogen atoms, an oxygen atom or a sulfur atom; .... means that R2 may be bonded to the atom on Ring B to form a ring, or their salts, and a method for producing them.