871728-33-5

Basic information

• Product Name: Carbamic acid, [(1R)-1-(3-methoxyphenyl)ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 871728-33-5
• Molecular Formula: C14H21NO3
• Molecular Weight: 251.326
• Mol File: 871728-33-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1R)-1-(3-methoxyphenyl)ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1R)-1-(3-methoxyphenyl)ethyl]-, 1,1-dimethylethyl ester(871728-33-5)
• EPA Substance Registry System: Carbamic acid, [(1R)-1-(3-methoxyphenyl)ethyl]-, 1,1-dimethylethyl ester(871728-33-5)

Safety Data

• Hazardous Substances Data: 871728-33-5(Hazardous Substances Data)

Upstream product

• 77-78-1 dimethyl sulfate 
• 266369-69-1 (R)-[1-(3-hydroxyphenyl)ethyl]carbamic acid tert-butyl ester 
• 121-71-1 3-Hydroxyacetophenone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1372628-56-2 3-((R)-1-((R)-1-phenylethylamino)ethyl)phenol 
• 88196-70-7 (R)-1-(3-methoxyphenyl)ethylamine 

Downstream Products

• 1006592-90-0 3-(2-chlorophenyl)-N-[(R)-1-(3-methoxyphenyl)ethyl]-2-propenamide 
• 1167414-89-2 (R)-1-(3-methoxyphenyl)ethanamine hydrochloride salt 
• 148717-49-1 tecalcet 
• 177172-48-4 (R)-3-(2-chlorophenyl)-N-(1-(3'-methoxyphenyl)ethyl)propanamide 
• 266369-69-1 (R)-[1-(3-hydroxyphenyl)ethyl]carbamic acid tert-butyl ester 
• 518060-42-9 (R)-1-(3-hydroxyphenyl)ethylamine 

Relevant articles and documents

General strategy for large-scale synthesis of (+)-rivastigmine and (+)-NPS R-568

An economically viable strategy for the total synthesis of (+)-rivastigmine and (+)-NPS R-568 has been reported. The strategy involves regioselective hydrogenation of diastereomerically pure bis amine to realize the desired a-methyl chiral substituted benzyl amine. The route is economical, scalable, and versatile enough to be adapted to similar classes of compounds. Taylor & Francis Group, LLC.