26691-62-3Relevant academic research and scientific papers
Phenanthrene Compound, Ramification Thereof And Drug Composition Containing Phenanthrene Compound Or Ramification And Used For Treating Tuberculosis
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Paragraph 0165; 0166; 0173, (2016/11/24)
The present invention relates to a novel phenanthrene compound, a ramification thereof and a drug composition containing the phenanthrene compound or the ramification and used for preventing or treating tuberculosis. The above tuberculosis activity resistant compound has excellent activity for the drug-fast MDR-MTB, also has a characteristic of low cytotoxicity, and can be used as the drug composition used for preventing or treating tuberculosis.
Stereospecific synthesis and biological evaluation of monodesmethyl metabolites of (+)-13a-(S)-deoxytylophorinine as potential antitumor agents
Yu, Pengfei,Lv, Haining,Li, Chao,Ren, Jinhong,Ma, Shuanggang,Xu, Song,Chen, Xiaoguang,Yu, Shishan
, p. 3757 - 3764 (2013/02/23)
Three major monodesmethyl metabolites of (+)-13a-(S)-deoxytylophorinine were synthesized stereospecifically and their configurations at C-13a were determined. Biological assays revealed that one of the metabolites, 3-O-desmethyl-13a-(S)-deoxytylophorinine
PHENANTHROINDOLIZIDINE DERIVATIVE AND NF B INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT
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Page/Page column 25, (2011/08/08)
A novel compound having an excellent NFκB inhibitory effect is provided. Specifically disclosed is a compound represented by the following formula (1) or a salt thereof: wherein, R1 represents a hydrogen atom, a lower alkyl group, or the like;
Asymmetric synthesis of phenanthroindolizidine alkaloids with hydroxyl group at the C14 position and evaluation of their antitumor activities
Ikeda, Takashi,Yaegashi, Takashi,Matsuzaki, Takeshi,Hashimoto, Syusuke,Sawada, Seigo
scheme or table, p. 342 - 345 (2011/02/27)
The asymmetric total synthesis of the strongly cytotoxic phenanthroindolizidine alkaloid 3 was achieved. Using the same route, various derivatives were also synthesized. Cytotoxicity of those synthetic compounds was evaluated and compounds 19, 23, and 27
