26847-68-7Relevant academic research and scientific papers
Stereospecific synthesis and biological evaluation of monodesmethyl metabolites of (+)-13a-(S)-deoxytylophorinine as potential antitumor agents
Yu, Pengfei,Lv, Haining,Li, Chao,Ren, Jinhong,Ma, Shuanggang,Xu, Song,Chen, Xiaoguang,Yu, Shishan
, p. 3757 - 3764 (2012)
Three major monodesmethyl metabolites of (+)-13a-(S)-deoxytylophorinine were synthesized stereospecifically and their configurations at C-13a were determined. Biological assays revealed that one of the metabolites, 3-O-desmethyl-13a-(S)-deoxytylophorinine
Phenanthroquinolizidine Phenanthroindolizidine alkaloid derivatives and salts thereof and their preparation, anti-plant-virus and anti-cancer activity
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Paragraph 0041; 0046, (2016/10/10)
Provided are phenanthroindolizidine alkaloid derivates and salt thereof as well as preparation, a plant-virus resisting activity, and an anti-cancer activity of phenanthroindolizidine alkaloid derivates and salt thereof. The derivates and the salt thereof have a good plant-virus resisting activity, which is capable of well restraining a tobacco mosaic virus (TMV), and meanwhile, have a good anti-cancer activity, which is capable of well restraining the human lung adenocarcinoma A-549 and the human leukemia HL-60.
