26786-28-7

Usage

Uses

Used in Organic Synthesis:
5-bromo-2-phenylpyrimidin-4-ol is used as a building block for the synthesis of various organic compounds. Its unique structure and properties make it a valuable component in the creation of new molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 5-bromo-2-phenylpyrimidin-4-ol is utilized as an intermediate in the synthesis of biologically active compounds. Its presence in these compounds can contribute to their therapeutic effects, making it a crucial component in drug development.
Used in Medicinal Chemistry:
5-bromo-2-phenylpyrimidin-4-ol is also used as a starting material for the development of new drugs. Its unique structure allows researchers to explore its potential in creating novel therapeutic agents that can address unmet medical needs.
Used in Drug Development:
5-bromo-2-phenylpyrimidin-4-ol's properties make it a candidate for further research in medicinal chemistry and drug development. Its potential applications in creating new drugs and improving existing ones highlight its importance in the pharmaceutical sector.

Upstream product

• 81560-03-4 2-methylsulfanyl-5-bromopyrimidin-4-one 
• 960-16-7 tributylphenylstannane 
• 33643-94-6 2-phenyl-4-hydroxypyrimidine 
• 15934-46-0 benzamidene hydrochloride 
• 33643-94-6 4-oxo-2-phenyl-3,4-dihydropyrimidine 

Downstream Products

• 26740-70-5 5-bromo-4-chloro-2-phenylpyrimidine 
• 27058-48-6 4-hydroxy-2-phenylpyrimidine-5-carbonitrile 
• 1266476-75-8 5-bromo-N-(5-cyclopropyl-2H-pyrazol-3-yl)-2-phenyl-pyrimidin-4-amine 
• 1266479-98-4 4,5-dibromo-2-phenylpyrimidine 

Relevant academic research and scientific papers

PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS

The present invention relates to compounds II useful as inhibitors of treating tuberculosis. The invention also provides processes for preparing compounds of the invention.

Desulfitative cross-coupling of protecting group-free 2-thiouracil derivatives with organostannanes

We here report a unique and efficient copper bromide mediated pallado-catalyzed coupling of protecting group-free 2-thiouracil derivatives with organostannanes. The nature of the copper appears to be crucial for successful cross coupling.

SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE

The present invention relates to pyridines, pyrimidines and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic beta cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.

PYRIMIDINES USEFUL AS MODULATORS OF VOLTAGE-GATED ION CHANNELS

The present invention relates to compounds useful as inhibitors of voltage-gated ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.