2683-49-0

Usage

Uses

Used in Pharmaceutical Industry:
4-Aminopyridine-2,6-dicarboxylic acid is used as a potential therapeutic target for various neurological disorders due to its neuroprotective and neurotoxic properties. It acts as an antagonist for the glycine site of the N-methyl-D-aspartate (NMDA) receptor, which is implicated in the pathophysiology of several neurological conditions.
Used in Neurological Disorder Treatment:
4-Aminopyridine-2,6-dicarboxylic acid is considered for the treatment of disorders such as epilepsy, schizophrenia, and neurodegenerative diseases. Its antagonistic action on the NMDA receptor may help in managing the symptoms and progression of these conditions.
Used in Anti-inflammatory and Antioxidant Applications:
4-Aminopyridine-2,6-dicarboxylic acid is used for its anti-inflammatory and antioxidant effects, which may contribute to the mitigation of inflammation and oxidative stress associated with various neurological disorders.
Used in Research and Development:
4-Aminopyridine-2,6-dicarboxylic acid is utilized in research settings to study its potential role in the treatment of neurological disorders. Ongoing studies aim to better understand its mechanisms of action and to explore its therapeutic potential in various conditions.

InChI:InChI=1/C7H6N2O4/c8-3-1-4(6(10)11)9-5(2-3)7(12)13/h1-2H,(H2,8,9)(H,10,11)(H,12,13)

Upstream product

• 4722-94-5 4-chloro-2,6-pyridinedicarboxylic acid 
• 150730-41-9 dimethyl 4-aminopyridine-2,6-dicarboxylate 
• 184870-12-0 chelidamic acid 
• 138-60-3 chelidamic acid 
• 71022-75-8 4-chloropyridine-2,6-dicarbonyl dichloride 
• 499-51-4 Chelidamic acid 
• 5371-70-0 dimethyl 4-chloro-2,6-pyridinedicarboxylate 
• 162102-82-1 4-acetylamino-pyridine-2,6-dicarboxylic acid 
• 179022-67-4 4-(acetylamino)-2,6-dimethylpyridine 

Downstream Products

• 73353-51-2 C₁₅H₁₈ClNO₇*C₈H₁₁N*ClHO₄ 
• 71124-59-9 C₁₅H₁₈ClNO₇*C₇H₉N*ClHO₄ 
• 71124-58-8 C₁₅H₁₈ClNO₇*C₇H₉N*CHNS 
• 504-24-5 4-aminopyridine 
• 63897-10-9 4-nitro-pyridine-2,6-dicarboxylic acid 
• 499-51-4 Chelidamic acid 

Relevant academic research and scientific papers

A Novel Reagent for Labelling Macromolecules with Intensely Luminescent Lanthanide Complexes

A novel bifunctional chelator, 4-iodoacetamidodipicolinic acid, has been synthesized in three steps starting with chelidamic acid, and used to prepare protein conjugates that form stable and intensely luminescent complexes with Tb(III) and Eu(III).The excited state lifetime of Tb(III) complexes with this reagent was 1.25 ms, permitting its use for ultrasensitive time-resolved luminescence assays.

Design and synthesis of complementary components for the formation of self-assembled supramolecular rigid rods

The complementary components AP2 and AU2, resulting respectively from the linking of diacylaminopyridine and uracil derivatives to an anthracenic core, have been designed in order to self-assemble, through hydrogen bonding, into polymeric supramolecular rigid rods (AP2, AU2)(n). The synthesis of these compounds is reported.

Selective cytotoxicity and luminescence imaging of cancer cells with a dipicolinato-based EuIII complex

Four new species [Ln(dipicNH2)3]3- (Ln = LaIII, EuIII, GdIII, TbIII), with the ligand dipicNH22- (dipic = dipicolinato), were synthesized. Incubation of the EuIII complex with glioma NG97 and pancreatic cancer PANC1 cells showed that it penetrates the cell membrane and can be used to image the cells, while also being moderately cytotoxic.

Modified Colorants and Inkjet Ink Compositions Comprising Modified Colorants

The present invention relates to a modified colorant comprising a colorant having attached at least one organic group. Various embodiments of the organic group are disclosed. For each of these embodiments, preferably the organic group has a defined calciu

Cation Complexing Properties of Synthetic Macrocyclic Polyether-Diester Ligands Containing the Pyridine Subcyclic Unit

Ten new macrocyclic polyether-diester compounds containing a pyridine subcyclic unit substituted in the 4 position with chloro or methoxy groups have been prepared.These compounds along with their unsubstituted pyridine analogues form strong complexes wit