269740-46-7

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 4-(hydroxyphenylmethyl)-, 1,1-dimethylethyl ester
• CAS NO: 269740-46-7
• Molecular Formula: C17H25NO3
• Molecular Weight: 291.39
• Mol File: 269740-46-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-(hydroxyphenylmethyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-(hydroxyphenylmethyl)-, 1,1-dimethylethyl ester(269740-46-7)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-(hydroxyphenylmethyl)-, 1,1-dimethylethyl ester(269740-46-7)

Safety Data

• Hazardous Substances Data: 269740-46-7(Hazardous Substances Data)

Usage

1-Piperidinecarboxylic acid, 4-(hydroxyphenylmethyl)-, 1,1-dimethylethyl ester

This is the chemical name of the compound tadalafil.

Erectile dysfunction and pulmonary arterial hypertension treatment

Tadalafil is used to treat these two medical conditions.

Relaxing muscles and increasing blood flow

Tadalafil works by relaxing the muscles and increasing blood flow to certain areas of the body.

Phosphodiesterase 5 (PDE5) inhibitor

Tadalafil specifically targets the enzyme that regulates blood flow in the penis and lungs.

Orally taken

Tadalafil is typically taken orally.

Longer duration of action

Tadalafil has a longer duration of action compared to other similar medications.

Prescription medication

Tadalafil is a prescription medication and should only be used under the guidance of a healthcare professional.

Upstream product

• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 100-58-3 phenylmagnesium bromide 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 100-59-4 phenylmagnesium chloride 
• 139290-70-3 tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 1126-09-6 4-carbethoxypiperidine 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 25503-90-6 1-acetyl-piperidine-4-carboxylic acid 
• 59084-16-1 1-acetylpiperidine-4-carbonyl chloride 
• 37586-22-4 4-benzoylpiperidine 
• 25519-80-6 4-(benzoyl)piperidine hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1557242-95-1 tert-butyl 4-((4-amino-1H-pyrazol-1-yl)(phenyl)methyl)piperidine-1-carboxylate 
• 1557234-04-4 6,6-dimethyl-N-(1-((R)-phenyl(piperidin-4-yl)methyl)-1H-pyrazol-4-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide 
• 1557234-07-7 6,6-dimethyl-N-(1-((S)-phenyl(piperidin-4-yl)methyl)-1H-pyrazol-4-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide 
• 1557249-48-5 C₃₆H₅₄N₆O₄Si 

Relevant articles and documents

Reductive Arylation of Amides via a Nickel-Catalyzed Suzuki–Miyaura-Coupling and Transfer-Hydrogenation Cascade

We report a means to achieve the addition of two disparate nucleophiles to the amide carbonyl carbon in a single operational step. Our method takes advantage of non-precious-metal catalysis and allows for the facile conversion of amides to chiral alcohols via a one-pot Suzuki–Miyaura cross-coupling/transfer-hydrogenation process. This study is anticipated to promote the development of new transformations that allow for the conversion of carboxylic acid derivatives to functional groups bearing stereogenic centers via cascade processes.

COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS

The present invention generally relates to compounds that are useful for inhibiting one or more trypsin-like S1 serine proteases, HGFA, matriptase, hepsin, KLK5 and/or TMPRSS2 as well as cysteine proteases including trypsin-like cysteine proteases (e.g. C

Iodonium ylides for one-step, no-carrier-added radiofluorination of electron rich arenes, exemplified with 4-(([18F]fluorophenoxy)- phenylmethyl)piperidine NET and SERT ligands

Iodonium ylide precursors of electron rich arenes, i.e. the NET and SERT ligands 4-((3- and 4-fluorophenoxy)phenylmethyl)piperidine, served as model compounds for the direct substitution with n.c.a. [18F]fluoride. Good radiochemical yields of a