270084-29-2

Basic information

• Product Name: 2-PHENYLBENZOYLACETONITRILE
• Synonyms: 2-PHENYLBENZOYLACETONITRILE
• CAS NO: 270084-29-2
• Molecular Formula: C15H11NO
• Molecular Weight: 221.25
• Mol File: 270084-29-2.mol

Chemical Properties

• Boiling Point: 430.5°Cat760mmHg
• Flash Point: 214.1°C
• Appearance: /
• Density: 1.128g/cm³
• Vapor Pressure: 1.29E-07mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: 2-PHENYLBENZOYLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYLBENZOYLACETONITRILE(270084-29-2)
• EPA Substance Registry System: 2-PHENYLBENZOYLACETONITRILE(270084-29-2)

Safety Data

• Hazardous Substances Data: 270084-29-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Phenylbenzoylacetonitrile is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the development of complex molecules that can be used in the creation of new drugs and therapeutic agents.
Used in Dye Industry:
As a building block, 2-Phenylbenzoylacetonitrile is used in the production of different types of dyes. Its reactivity and structural properties contribute to the development of novel dyes with improved characteristics.
Used in Agrochemical Industry:
2-Phenylbenzoylacetonitrile is utilized as a starting material in the synthesis of various agrochemicals. Its role in creating complex molecules aids in the development of new pesticides, herbicides, and other agricultural chemicals.
Used in Organic Electronics and Materials Science:
2-Phenylbenzoylacetonitrile has potential applications in the field of organic electronics and materials science. Its unique properties make it a promising candidate for use in the development of advanced materials and electronic components.

InChI:InChI=1/C15H11NO/c16-11-10-15(17)14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-9H,10H2

Upstream product

• 2142-66-7 1-([1,1'-biphenyl]-2-yl)ethanone 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 100-59-4 phenylmagnesium chloride 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 16605-99-5 biphenyl-2-carboxylic acid methyl ester 
• 75-05-8 acetonitrile 

Relevant articles and documents

Rhodium-catalyzed cyclization of acceptor-substituted biphenyl α-diazoketones: A study of the substitution effect on chemoselectivity

A range of biphenyl α-diazoketones containing various electron-withdrawing groups (EWG = COCH3, CN, CO2Et, COPh, SO2CH3, SO2Ph) on diazo carbon has been investigated for rhodium(ii)-catalyzed intramol

N-Iodosuccinimide and dioxygen in an air-enabled synthesis of 10-phenanthrenols under sunlight

Using a catalytic amount ofN-iodosuccinimide (NIS) in combination with O2in air, an aerobic oxidative reaction was carried out to efficiently and scalably construct a series of 10-phenanthrenols under sunlight at room temperature. Mechanistic studies reveal that H2O2generatedin situwas responsible for the conversion of I2to IOH as a potential initiator for later catalytic cycle.

N-Bromosuccinimide-Induced C-H Bond Functionalization: An Intramolecular Cycloaromatization of Electron Withdrawing Group Substituted 1-Biphenyl-2-ylethanone for the Synthesis of 10-Phenanthrenol

An NBS-induced intramolecular cycloaromatization for the synthesis of 10-phenanthrenols from electron-withdrawing group substituted 1-biphenyl-2-ylethanones is described. The in situ generated bromide was designed to act as an initiator for the radical C-H bond activation. An oxidative cross-dehydrogenative coupling reaction of a highly active C-H bond with an inert C-H bond readily occurs under mild conditions without the need for transition metals or strong oxidants.

Pyrazolotriazines as inhibitors of nucleases

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3 and R4 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.