270088-53-4

Basic information

• Product Name: Acridine, 3-chloro-9-[(4-nitrophenyl)thio]-
• CAS NO: 270088-53-4
• Molecular Formula: C19H11ClN2O2S
• Molecular Weight: 366.828
• Mol File: 270088-53-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acridine, 3-chloro-9-[(4-nitrophenyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acridine, 3-chloro-9-[(4-nitrophenyl)thio]-(270088-53-4)
• EPA Substance Registry System: Acridine, 3-chloro-9-[(4-nitrophenyl)thio]-(270088-53-4)

Safety Data

• Hazardous Substances Data: 270088-53-4(Hazardous Substances Data)

Upstream product

• 95112-15-5 6-Chloro-9-thioacridone 
• 586-78-7 para-nitrophenyl bromide 
• 6269-27-8 3-chloroacridin-9(10H)-one 
• 118-91-2 ortho-chlorobenzoic acid 
• 13278-36-9 N-(3-chlorophenyl)anthranilic acid 
• 108-42-9 3-chloro-aniline 
• 62-53-3 aniline 
• 50-84-0 2,4 dichlorobenzoic acid 
• 19218-88-3 N-phenyl-4-chloroanthranilic acid 

Relevant articles and documents

Inhibition of Cryptosporidium parvum in vitro by 9-(alkylthio)acridine derivatives

The synthesis of several acridinic thioethers is described. Compounds prepared were tested in vitro as potential drugs against the opportunistic infection known as cryptosporidiosis. With a view to predict activity, the quantitative structure-activity relationships were investigated. Correlations between experimental data and either log P or pKa are discussed.

Structure-trypanodical activity relationships

A set of 9-thioalkylacridinones, has been prepared and investigated' in vitro' against T. cruzi. Structure-antiparasitic activity relationships are detailed with a view to identify the major structural parameters for the activity under consideration.