6269-27-8

Basic information

• Product Name: 3-Chloro-9(10H)-acridinone
• Synonyms: 3-Chloro-9(10H)-acridinone
• CAS NO: 6269-27-8
• Molecular Formula: C₁₃H₈ClNO
• Molecular Weight: 229.66
• Mol File: 6269-27-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 390.6°C at 760 mmHg
• Flash Point: 190°C
• Appearance: /
• Density: 1.346g/cm³
• Vapor Pressure: 2.63E-06mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 3-Chloro-9(10H)-acridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-9(10H)-acridinone(6269-27-8)
• EPA Substance Registry System: 3-Chloro-9(10H)-acridinone(6269-27-8)

Safety Data

• Hazardous Substances Data: 6269-27-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H8ClNO/c14-8-5-6-10-12(7-8)15-11-4-2-1-3-9(11)13(10)16/h1-7H,(H,15,16)

Upstream product

• 50433-64-2 3-amino-10H-acridin-9-one 
• 5551-11-1 4-Chloro-2-nitrobenzaldehyde 
• 14313-60-1 6-chlorobenzo[c]isoxazole? 
• 98-80-6 phenylboronic acid 
• 5900-58-3 2-amino-4-chloro-benzoic acid methyl ester 
• 66003-76-7 Diphenyliodonium triflate 
• 108-42-9 3-chloro-aniline 
• 118-91-2 ortho-chlorobenzoic acid 
• 92044-38-7 3-chloro-9,10-dihydro-acridine 
• 62-53-3 aniline 
• 50-84-0 2,4 dichlorobenzoic acid 
• 71-43-2 benzene 
• 108-90-7 chlorobenzene 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 70974-00-4 10-benzyl-3-chloroacridin-9(10H)-one 
• 3407-98-5 5-Amino-2-chloroacridin 
• 270088-53-4 3-Chloro-9-(4-nitro-phenylsulfanyl)-acridine 
• 35547-70-7 3,9-dichloroacridine 
• 59304-30-2 6-chloroacridine 

Relevant articles and documents

Access to acridones by tandem copper(i)-catalyzed electrophilic amination/Ag(i)-mediated oxidative annulation of anthranils with arylboronic acids

An efficient and practical approach for the synthesis of medicinally important acridones was developed from anthranils and commercially available arylboronic acids by a tandem copper(i)-catalyzed electrophilic amination/Ag(i)-mediated oxidative annulation strategy. This new and straightforward protocol displayed a broad substrate scope (25 examples) and high functional group tolerance. What's more, a possible mechanistic proposal was also presented.

Transition-Metal-Free Synthesis of Acridones via Base-Mediated Intramolecular Oxidative C?H Amination

Intramolecular oxidative C?H amination of 2-aminobenzophenones was achieved in the presence of potassium tert-butoxide and dimethyl sulfoxide. A series of functionalized acridones were prepared in moderate to excellent yields in a mild, efficient, and transition-metal-free manner. (Figure presented.).

Tandem arylation/friedel-crafts reactions of o-acylanilines with diaryliodonium salts: A modular synthesis of acridine derivatives

A modular method to synthesize acridine derivatives was developed with o-acylanilines and diaryliodonium salts. The reactions proceeded smoothly under Cu-catalyzed or metal-free reaction conditions at elevated temperature through tandem arylation/Friedel-Crafts reactions.