27074-03-9

Basic information

• Product Name: 1,4-Dimethyl-3-cyano-6-hydroxypyrid-2-one
• Synonyms: 1,4-DIMETHYL-3-CYANO-6-HYDROXY PYRIDONE;N-METHYL-3-CYANO-6-HYDROXY-4-METHYL-2-PYRIDONE;TIMTEC-BB SBB000150;1,2-dihydro-1,4-dimethyl-2-oxo-3-pyridinecarbonitril;1,2-dihydro-1,4-dimethyl-6-hydroxy-2-oxo-nicotinonitril;1,2-dihydro-1,4-dimethyl-6-hydroxy-2-oxonicotinonitrile;1,2-dihydro-6-hydroxy-1,4-dimethyl-2-oxo-3-pyridinecarbonitril;1,2-dihydro-6-hydroxy-1,4-dimethyl-2-oxo-3-Pyridinecarbonitrile
• CAS NO: 27074-03-9
• Molecular Formula: C₈H₈N₂O₂
• Molecular Weight: 164.16
• EINECS: 248-209-8
• Product Categories: Heterocycle-Pyridine series
• Mol File: 27074-03-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 275-277 °C
• Boiling Point: 304.5 °C at 760 mmHg
• Flash Point: 137.9 °C
• Appearance: /
• Density: 1.32 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.77±0.58(Predicted)
• CAS DataBase Reference: 1,4-Dimethyl-3-cyano-6-hydroxypyrid-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dimethyl-3-cyano-6-hydroxypyrid-2-one(27074-03-9)
• EPA Substance Registry System: 1,4-Dimethyl-3-cyano-6-hydroxypyrid-2-one(27074-03-9)

Safety Data

• Hazardous Substances Data: 27074-03-9(Hazardous Substances Data)

Usage

Uses

2-Hydroxy-1,4-dimethyl-5-cyano-6-pyridinon is used in the synthesis of many azo dyes.

InChI:InChI=1/C8H8N2O2/c1-5-3-7(11)10(2)8(12)6(5)4-9/h3,11H,1-2H3

Upstream product

• 6330-25-2 N-methyl-2-cyanoacetamide 
• 105-45-3 acetoacetic acid methyl ester 
• 74-89-5 methylamine 
• 105-34-0 methyl 2-cyanoacetate 
• 105-56-6 ethyl 2-cyanoacetate 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 85843-03-4 6-hydroxy-1,4-dimethyl-5-(4-morpholinylmethyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 85843-04-5 6-hydroxy-1,4-dimethyl-5-(4-phenyl-1-piperazinylmethyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 75511-98-7 1,2-dihydro-1,4-dimethyl-6-hydroxy-2-oxo-5-phenylazopyridine-3-carbonitrile 
• 72570-56-0 3-Methyl-1-oxo-1H,5H-pyrido<1,2-a>benzimidazole 
• 329348-61-0 6-Chloro-3-cyano-5-formyl-1,4-dimethylpyridin-2(1H)-one 
• 79926-29-7 3-Methyl-1,4-dioxopyrido<1,2-a>benzimidazole-4-p-tolyl-hydrazone 
• 79926-31-1 3-Methyl-1,4-dioxopyrido<1,2-a>benzimidazole-4-p-chlorophenyl-hydrazone 
• 79926-33-3 3-Methyl-1,2-dioxopyrido<1,2-a>benzimidazole-2-p-tolyl-hydrazone 
• 79926-35-5 3-Methyl-1,2-dioxopyrido<1,2-a>benzimidazole-2-p-chlorophenyl-hydrazone 
• 79926-34-4 3-Methyl-1,2-dioxopyrido<1,2-a>benzimidazole-2-(4'-methoxyphenyl)-hydrazone 
• 79926-30-0 3-Methyl-1,4-dioxopyrido<1,2-a>benzimidazole-4-(4'-methoxyphenyl)-hydrazone 

Relevant articles and documents

An Efficient Method for the Synthesis of 3-Cyano-6-hydroxy-2(1H)- pyridinones under Microwave Irradiation and Solvent-free Conditions

Three component condensation of alkylacetoacetates, primary amines, and alkyl cyanoacetates catalyzed by solid supports under microwave irradiation gave N-alkyl 3-cyano-6-hydroxy-2(1H)-pyridinones with high yields. Upon carrying out the reaction under the same condition on acidic alumina, zeolite HY, silica gel, and montmorillonite K-10, the best yields were achieved by silica gel.

Azo pyridone dyestuffs containing at least one reactive phosphoric or phosphonic acid group

Azo pyridone dyestuffs containing at least one reactive phosphoric or phosphonic acid group. The dyestuffs are characterized by the formula: wherein A is an aromatic radical containing at least one phosphoric or phosphonic acid group and R is a monovalent radical derived from a pyridone coupling component by removing a hydrogen atom attached to a ring carbon atom of the pyridone ring. The aromatic radical A is preferably a phenyl or naphthyl group. In addition to its phosphonic or phosphoric acid group or groups, radical A may be substituted with one or more halogen, alkyl, alkoxy, nitro, sulfonic acid or carboxylic acid groups. Cellulosic textiles, e.g., cotton or cotton/polyester blends, may be reactively dyed with these dyestuffs in an acid, neutral or alkaline bath using dicyandiamide or the equivalent. The phosphoric or phosphonic acid groups and the cellulosic material react to fix the dye through an ester linkage. Examples of suitable dyestuffs include those having the formula: STR1 and STR2