2708-87-4

Upstream product

• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 762-04-9 phosphonic acid diethyl ester 
• 2314-97-8 iodotrifluoromethane 
• 122-52-1 triethyl phosphite 

Downstream Products

• 1207475-14-6 diethyl 3-phenyl-1-trifluoromethylpropyl phosphate 
• 101396-02-5 1-(β-phenylethyl)-2,2,2,-trifluoroethanol 
• 379-18-0 1,1-diphenyl-2,2,2-trifluoroethanol 
• 120747-41-3 9-(trifluoromethyl)-9-fluorenol 
• 5173-02-4 phenyl trifluoromethylselenide 
• 340-04-5 1-phenyl-2,2,2-trifluoromethylethanol 
• 456-56-4 phenyl trifluoromethylsulfide 
• 630-71-7 4,4'-dichloro-α-phenyl-α-(trifluoromethyl)benzenemethanol 

Relevant academic research and scientific papers

Copper-catalyzed aerobic oxidative trifluoromethylation of h-phosphonates using trimethyl(trifluoromethyl)silane

Copper-catalyzed aerobic oxidative trifluoromethylation of readily accessible H-phosphonates was demonstrated for the first time. This method not only provides an alternative method for the facile synthesis of a series of biologically important CFphosphonates, but also demonstrates the first example of the efficient construction of a P-CFbond via transition-metal catalysis.

SIMPLE PREPARATION OF DIALKYL POLYFLUOROALKYL PHOSPHONATES

Several dialkyl polyfluoroalkyl phosphonates can be prepared by reacting trialkyl phosphites with trifluoromethyl iodide or dibromodifluoromethane under pressure and/or photolytic conditions.The resulting phosphonates are precursors to the corresponding phosphonic acids.