27182-54-3

Usage

Uses

Used in Medicinal Chemistry:
5-PHENYL-1,2,4-THIADIAZOL-3-AMINE is used as a key intermediate in the synthesis of pharmaceutical drugs for its potential to exhibit biological activity. Its unique structure allows for the development of derivatives with specific pharmacological properties, making it a valuable component in drug discovery and design.
Used in Drug Development:
In the pharmaceutical industry, 5-PHENYL-1,2,4-THIADIAZOL-3-AMINE serves as a building block for creating new drug candidates. Its incorporation into molecular structures can lead to the discovery of novel therapeutic agents with improved efficacy and selectivity for various medical conditions.
Used in Chemical Research:
5-PHENYL-1,2,4-THIADIAZOL-3-AMINE is utilized in scientific research to investigate its chemical properties and reactivity. Understanding its behavior in different chemical reactions can provide insights into the development of new synthetic routes and applications in material science.
Used in Material Science:
5-PHENYL-1,2,4-THIADIAZOL-3-AMINE may also find applications in material science, where its unique structural features could contribute to the development of new materials with specific properties, such as improved conductivity, stability, or responsiveness to environmental stimuli.
Overall, the versatility of 5-PHENYL-1,2,4-THIADIAZOL-3-AMINE in various applications underscores its importance in the fields of chemistry, pharmaceuticals, and materials science, with ongoing research continuing to uncover new potential uses and properties.

InChI:InChI=1/C8H7N3S/c9-8-10-7(12-11-8)6-4-2-1-3-5-6/h1-5H,(H2,9,11)

Upstream product

• 101495-43-6 3-bromo-5-phenyl-1,2,4-thiadiazole 
• 7746-72-7 N¹-benzoyl-N³-cyanoguanidine 
• 7746-72-7 Benzoyldicyandiamid 
• 10349-15-2 3-(Acetylamino)-4-phenylfurazan 
• 160694-84-8 (E)-3-benzoyl-5-methyl-1,2,4-thiadiazol oxime 
• 89880-02-4 N-(Imino-ureido-methyl)-thiobenzamide 
• 89880-02-4 N-carbamoyl-N'-thiobenzoylguanidine 
• 3166-00-5 benzoylguanidine 
• 936-61-8 Thiobenzoic acid O-ethyl ester 
• 5699-40-1 acetylguanidine 
• 63980-64-3 benzoylcarbamimidoyl-thiourea 

Downstream Products

• 101352-09-4 N-acetyl-sulfanilic acid-(5-phenyl-[1,2,4]thiadiazol-3-ylamide) 
• 93333-09-6 4-acetylamino-N-(5-phenyl-[1,2,4]thiadiazol-3-ylcarbamoyl)-benzenesulfonamide 
• 93534-88-4 (5-phenyl-[1,2,4]thiadiazol-3-yl)-carbamic acid ethyl ester 
• 27185-76-8 (5-phenyl-[1,2,4]thiadiazol-3-yl)-trityl-amine 
• 92432-67-2 benzylidene-(5-phenyl-[1,2,4]thiadiazol-3-yl)-amine 
• 27182-70-3 4,4'-dinitro-N-(5-phenyl-[1,2,4]thiadiazol-3-yl)-dibenzamide 
• 27182-73-6 S-(2-nitro-phenyl)-N-(5-phenyl-[1,2,4]thiadiazol-3-yl)-thiohydroxylamine 
• 27182-74-7 bis-(2-nitro-phenylsulfanyl)-(5-phenyl-[1,2,4]thiadiazol-3-yl)-amine 
• 92427-03-7 1-(3,4-dichloro-benzenesulfonyl)-3-(5-phenyl-[1,2,4]thiadiazol-3-yl)-urea 
• 27185-75-7 benzhydryl-(5-phenyl-[1,2,4]thiadiazol-3-yl)-amine 
• 93021-02-4 1-(5-phenyl-[1,2,4]thiadiazol-3-yl)-3-(toluene-4-sulfonyl)-urea 
• 92428-19-8 1-(4-chloro-benzenesulfonyl)-3-(5-phenyl-[1,2,4]thiadiazol-3-yl)-urea 
• 27182-68-9 3-methyl-N-(5-phenyl-[1,2,4]thiadiazol-3-yl)-benzamide 
• 27182-69-0 3,3'-dimethyl-N-(5-phenyl-[1,2,4]thiadiazol-3-yl)-dibenzamide 

Relevant academic research and scientific papers

Facile synthesis of substituted 5-amino- And 3-amino-1,2,4-thiadiazoles from a common precursor

[Chemical Equation Presented] A novel approach to the synthesis of substituted 5-amino- and 3-amino-1,2,4-thiadiazoles beginning from a common precursor has been achieved. Derivatization by palladium-catalyzed Suzuki-Miyaura coupling enables the rapid pre

Molecular Rearrangements in Heterocyclic Synthesis. A Generalized Synthesis of 1,2,4-Thiadiazoles from 3-Acylamino-1-oxa-2-azoles

The sulfurization reaction of some 3-acylamino-1-oxa-2-azoles (1,2,4-oxadiazoles, isoxazoles and 1,2,5-oxadiazoles) with the Lawesson reagent has been investigated.A generalized methodology for the synthesis of 5-aryl-/alkyl-3-substituted 1,2,4-thiadiazol

A New Ring Interconversion: 3-Azido-1,2,4-thiadiazoles from the Reaction of Thionyl Chloride with 1-Alkyl-5-aminotetrazoles

Heating of some 1-alkyl-5-aminotetrazoles with thionyl chloride gave 3-azido-1,2,4-thiadiazoles in a reaction involving 5-N-sulphinylaminotetrazoles as intermediates.

Cyclic Meso-ionic Compounds. Part 23. Novel Chemistry of 1,2,4-Thiadiazoles and Their Transformation into Meso-ionic 1,2,4-Thiadiazolium Derivatives

Representatives of two new classes of meso-ionic heterocycles have been synthesised, the 1,2,4-thiadiazolium-3-olate (8) and the 1,2,4-thiadiazolium-3-tosylaminide (25).The reactions of 1,2,4-thiadiazoles and nucleophiles follow two general pathways: (i) reductive transformation to N-thiobenzoyl derivatives and (ii) elimination of elemental sulphur and the formation of N-benzoyl derivatives.A mechanistic rationale is proposed for the operation of pathways (i) and (ii).Earlier views on the oxidative formation of certain 1,2,4-thiadiazoles are corrected.A novel synthetic route to heterocycles containing sulphur-nitrogen bonds is described. 1,2,4-Thiadiazoles are formed by oxidation of N-thiobezoylureas and N-thiobenzoylguanidines by bis(4-methoxyphenyl) telluroxide.