27285-20-7Relevant academic research and scientific papers
Ru-Catalyzed Deoxygenative Transfer Hydrogenation of Amides to Amines with Formic Acid/Triethylamine
Pan, Yixiao,Luo, Zhenli,Xu, Xin,Zhao, Haoqiang,Han, Jiahong,Xu, Lijin,Fan, Qinghua,Xiao, Jianliang
supporting information, p. 3800 - 3806 (2019/07/12)
A ruthenium(II)-catalyzed deoxygenative transfer hydrogenation of amides to amines using HCO2H/NEt3 as the reducing agent is reported for the first time. The catalyst system consisting of [Ru(2-methylallyl)2(COD)], 1,1,1-tris(diphenylphosphinomethyl) ethane (triphos) and Bis(trifluoromethane sulfonimide) (HNTf2) performed well for deoxygenative reduction of various secondary and tertiary amides into the corresponding amines in high yields with excellent selectivities, and exhibits high tolerance toward functional groups including those that are reduction-sensitive. The choice of hydrogen source and acid co-catalyst is critical for catalysis. Mechanistic studies suggest that the reductive amination of the in situ generated alcohol and amine via borrowing hydrogen is the dominant pathway. (Figure presented.).
One-pot reductive mono-n-alkylation of aromatic nitro compounds using nitriles as alkylating reagents
Neogi, Subhasish,Naskar, Dinabandhu
experimental part, p. 1901 - 1915 (2011/07/08)
A one-pot, simple, selective, and efficient protocol for the synthesis of aromatic secondary amines from various nitro arenes and nitriles in the presence of 10% Pd/C catalyst under H2 at atmospheric pressure and ambient temperature in tetrahydrofuran is illustrated. The scope and limitations of this method have been examined.
1H, 2H, 19F, 14N ENDOR and TRIPLE Resonance Investigations of Substituted Flavin Radicals in Their Different Protonation States
Weilbacher, E.,Helle, N.,Elsner, M.,Kurreck, H.,Mueller, F.,Allendoerfer, R. D.
, p. 64 - 72 (2007/10/02)
A variety of isotopically labelled and/or substituted flavins have been converted into their corresponding radical states.Cation and neutral radicals were generated chemically and anion radicals were obtained electrochemically.By performing ENDOR and TRIPLE resonance experiments, complete sets of hyperfine coupling constants including their signs were accessible.The hyperfine data allowed (a) identification of the radical state present, (b) information to be obtained about the preferred conformational arrangements of the substituents and (c) conclusions to be drawn about the influences of the substituents on the spin density distributions of the different radical states. - KEY WORDS: ENDOR, TRIPLE resonance spectroscopy; Flavin radicals; Electrochemical generation of radicals.
