27301-54-8Relevant articles and documents
Total synthesis of 2′-O-methylmyxalamide D and (6E)-2′-O- methylmyxalamide D
Coleman, Robert S.,Lu, Xiaoling,Modolo, Isabelle
, p. 3826 - 3827 (2007)
Hetero-bis-metalated 1,3,5-hexatrienes are employed in the linchpin coupling of synthetic fragments for the convergent construction of the central pentaene of the antifungal agent 2′-O-methylmyxalamide D and its (6E) isomer. Sequential Stille and Suzuki-Miyaura couplings interpolate the boron/tin triene into the pentaene chain. The total synthesis of O-methylmyxalamide D and its (6E) isomer was accomplished efficiently. Copyright
Convenient generation of 1-propynyllithium. One-pot synthesis of acetylenic carbinols from 1,2-dibromopropane and aldehydes and ketones
Gribble,Joyner,Switzer
, p. 2997 - 3002 (1992)
Treatment of 1,2-dibromopropane (1) with 3 equiv of lithium diisopropylamide (-60° to 0°C, THF) generates 1-propynyllithium (2), which with aldehydes or ketones affords acetylenic carbinols 3 in 82-96% yields.
Synthesis and characterization of all four diastereomers of 3,4-dichloro-2-pentanol, motifs relevant to the chlorosulfolipids
Kanady, Jacob S.,Nguyen, John D.,Ziller, Joseph W.,Vanderwal, Christopher D.
, p. 2175 - 2178 (2009)
All four diastereomers of 3,4-dichloro-2-pentanol were synthesized by anti-dichlorination of the precursor allylic alcohols; their stereochemistry was elucidated by X-ray crystallographic analysis of tosylate derivatives. Complete NMR data is provided in
Stereoselective Synthesis of the C1-C22 Carbon Framework of (-)-Amphidinolide K
Chandankar, Somnath S.,Raghavan, Sadagopan
, p. 9584 - 9602 (2019/09/06)
Two stereoselective routes to the C7-C22 subunit of amphidinolide K are disclosed. Jacobsen's hydrolytic kinetic resolution and Sharpless' asymmetric dihydroxylation reactions have been employed for the construction of the tetrahydrofuran ring. The C10-C1
MACROCYCLIC PICOLINAMIDES AS FUNGICIDES
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Paragraph 0098; 0099, (2016/01/25)
This disclosure relates to macrocyclic picolinamides of Formula (I) described herein, wherein X, Y, R1 and R2 are as defined herein and to their use as fungicides in a formulation comprising a phytologically acceptable carrier. Also provided are methods of using compounds of Formula (I) in combination with other pesticides including fungicides, insecticides, nematocides, miticides, arthropodicides, bactericides, and combinations thereof.