27331-02-8

Basic information

• Product Name: 2-(1-Methylcyclohexyl)-2-propanol
• Synonyms: 2-(1-Methylcyclohexyl)-2-propanol
• CAS NO: 27331-02-8
• Molecular Formula: C₁₀H₂₀O
• Molecular Weight: 156.2652
• Mol File: 27331-02-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 144.3 °C(Press: 100 Torr)
• Appearance: /
• Density: 0.93929 g/cm3
• PKA: 15.18±0.29(Predicted)
• CAS DataBase Reference: 2-(1-Methylcyclohexyl)-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Methylcyclohexyl)-2-propanol(27331-02-8)
• EPA Substance Registry System: 2-(1-Methylcyclohexyl)-2-propanol(27331-02-8)

Safety Data

• Hazardous Substances Data: 27331-02-8(Hazardous Substances Data)

Usage

Physical State

Colorless liquid

Odor

Mild

Solubility

Soluble in both water and organic solvents

Uses

+ Solvent in various industrial applications
+ Production of pharmaceuticals, agrochemicals, and specialty chemicals
+ Co-solvent in cleaning products
+ Chemical intermediate in the synthesis of other compounds

Toxicity

Low toxicity, not expected to be harmful under normal use and handling

Safety Precautions

Follow proper safety measures when working with TMOH.

Upstream product

• 6555-61-9 1-(1-methylcyclohexyl)ethan-1-ol 
• 6493-80-7 methyl 1-methyl-3-cyclohexenecarboxylate 
• 917-64-6 methyl magnesium iodide 
• 825-04-7 methyl 1-methylcyclohexanecarboxylate 
• 2890-62-2 methyl 1-methylcyclohexyl ketone 
• 75295-91-9 1-Chlor-1-tert.-butylcyclohexan 
• 6555-60-8 1-(1-methyl-cyclohex-3-enyl)-ethanol 
• 917-54-4 methyllithium 

Downstream Products

• 16580-26-0 1-methyl-1-isopropylcyclohexane 
• 16580-19-1 1-Methyl-1-(1-methylethenyl)cyclohexane 

Relevant articles and documents

Some studies on the solvolysis of 1-chloro-1-alkyl cycloalkanes

The effect of the bulk of the sidechain on the rate of solvolysis of 1-alkyl cyclopentyl, cyclohexyl, and cycloheptyl chlorides has been studied.With the exception of the t-butyl systems, the ratio of solvolysis rates for the three ring systems falls in a given series.The slower rate of solvolysis in the six-membered ring system may be due to an extra activation energy contribution caused by the conversion of a neutral chair form to the twist boat or half chair conformation, prior to the actual solvolysis.In the case of five- and seven-membered ring systems the formation of an intermediate carbonium ion is sterically favoured (I-strain or eclipsing interaction) consistent with earlier findings.The faster rate of solvolysis of 1-t-butylcycloalkyl chlorides is likely due to a rearrangement reaction where alkyl participation enhances the rate of solvolysis.