273408-90-5

Usage

Uses

Used in Pharmaceutical Industry:
2-Pyridin-3-yl-quinazolin-4-ylamine is used as a potential drug candidate for the development of new medications due to its ability to interact with biological systems and exhibit pharmacological activity.
Used in Medicinal Chemistry Research:
2-Pyridin-3-yl-quinazolin-4-ylamine is used as a subject of study in medicinal chemistry research to explore its potential applications and understand its interactions with biological systems.
Used in Drug Discovery:
2-Pyridin-3-yl-quinazolin-4-ylamine is used as a starting point for drug discovery efforts, as its unique structure and properties may lead to the development of novel therapeutic agents.
Used in Biochemical Studies:
2-Pyridin-3-yl-quinazolin-4-ylamine is used in biochemical studies to investigate its interactions with biological molecules and understand its potential role in various biological processes.

InChI:InChI=1/C13H10N4/c14-12-10-5-1-2-6-11(10)16-13(17-12)9-4-3-7-15-8-9/h1-8H,(H2,14,16,17)

Upstream product

• 100-54-9 pyridine-3-carbonitrile 
• 1885-29-6 anthranilic acid nitrile 
• 59-67-6 nicotinic acid 
• 500-22-1 3-pyridinecarboxaldehyde 
• 2042-37-7 o-cyanobromobenzene 
• 15432-24-3 2-(pyridin-3-yl)-indole 
• 4387-36-4 2-iodobenzonitrile 
• 885953-16-2 2-iodobenzimidamide 

Downstream Products

• 280570-45-8 VUF 5574 

Relevant academic research and scientific papers

RECEPTOR TYROSINE KINASE INHIBITORS FOR TREATMENT OF PROTEIN KINASE MODULATION-RESPONSIVE DISEASE OR DISORDER

Ephrin type receptor tyrosine kinase inhibitors, also known as Eph tyrosine kinase receptor inhibitors, for treating cancer, an inflammatory disease, an autoimmune disease, or a degenerative disease characterized at least in part by the abnormal activity

Efficient synthesis of 2-arylquinazolin-4-amines via a copper-catalyzed diazidation and ring expansion cascade of 2-arylindoles

Copper-catalyzed synthesis of 2-arylquinazolin-4-amines from readily available 2-arylindoles and TMSN3 has been developed. The mechanism study shows that the domino reaction may involve a free radical diazidation, denitrogenation, intramolecular cyclization and ring expansion sequence.

A Highly Efficient Copper-Catalyzed Three-Component Synthesis of 4-Aminoquinazolines

A highly efficient copper-catalyzed one-pot protocol is developed for the synthesis of 4-aminoquinazolines from easily available 2-iodo- or 2-bromobenzimidamides, aldehydes, and sodium azide. This one-pot approach proceeds via consecutive copper-catalyzed SNAr substitution, reduction, cyclization, oxidation and tautomerization. The corresponding target products (26 examples) are obtained in 50-90% yield.

Expeditious Synthesis of 2-Phenylquinazolin-4-amines via a Fe/Cu Relay-Catalyzed Domino Strategy

A highly efficient Fe/Cu relay-catalyzed domino protocol has been developed for the synthesis of 2-phenylquinazolin-4-amines from commercially available ortho-halogenated benzonitriles, aldehydes, and sodium azide. This elegant domino process involved con

An efficient method to prepare 4-aminoquinazolines: Potential application to conformation-restricted bleomycin analogs

(Chemical Equation Presented) To enhance the iron-chelating ability of P-3A, 4-aminoquinazolines were designed as conformation-restricted bleomycin analogs. An efficient method was developed to prepare the 4-aminoquinazoline heterocyclic nucleus, which en

Isoquinoline and quinazoline urea analogues as antagonists for the human-adenosine A3 receptor

Isoquinoline and quinazoline urea derivatives were found to bind to human adenosine AS receptors. Series of N-phenyl-N'-quinazolin-4-ylurea derivatives and N-phenyl-N'-isoquinolin-1-ylurea derivatives were synthesized and tested in radioligand binding ass

Microwave enhanced synthesis of 4-aminoquinazolines

Cyanoaromatic compounds react with anthranilonitrile in a domestic microwave oven affording good yields of the corresponding 4-aminoquinazolines in a very short irradiation time. (C) 2000 Elsevier Science Ltd.