27361-16-6

Basic information

• Product Name: 2-N-BUTOXYPYRIDINE
• Synonyms: 2-BUTOXYPYRIDINE;2-N-BUTOXYPYRIDINE;N-BUTYL 2-PYRIDYL ETHER;butyl 2-pyridyl ether;2-n-Butoxypyridine,95%;2-Butoxypyridine,98%;2-Butoxypyridine SynonyMs NSC 30253;NSC 30253
• CAS NO: 27361-16-6
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.21
• EINECS: 248-428-9
• Mol File: 27361-16-6.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 200 °C(lit.)
• Flash Point: 167 °F
• Appearance: /
• Density: 0.975 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.469mmHg at 25°C
• Refractive Index: n20/D 1.492(lit.)
• PKA: 4.13±0.12(Predicted)
• CAS DataBase Reference: 2-N-BUTOXYPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-N-BUTOXYPYRIDINE(27361-16-6)
• EPA Substance Registry System: 2-N-BUTOXYPYRIDINE(27361-16-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 27361-16-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H13NO/c1-2-3-8-11-9-6-4-5-7-10-9/h4-7H,2-3,8H2,1H3

Upstream product

• 110-86-1 pyridine 
• 71-36-3 butan-1-ol 
• 109-09-1 2-chloropyridine 
• 142-08-5 2-hydroxypyridin 
• 5029-67-4 2-iodopyridine 
• 109-65-9 1-bromo-butane 
• 85100-77-2 1-n-butyl-3-methylimidazolim bromide 
• 874-80-6 1-butylpyridinium bromide 
• 778-28-9 butyl para-toluenesulfonate 
• 542-69-8 1-iodo-butane 
• 109-69-3 n-Butyl chloride 
• 109-04-6 2-bromo-pyridine 
• 1120-90-7 3-iodopyridine 
• 66-71-7 1,10-Phenanthroline 

Downstream Products

• 6627-95-8 2-butoxy-5-nitro-pyridine 

Relevant articles and documents

Light-Promoted Nickel Catalysis: Etherification of Aryl Electrophiles with Alcohols Catalyzed by a NiII-Aryl Complex

A highly effective C?O coupling reaction of (hetero)aryl electrophiles with primary and secondary alcohols is reported. Catalyzed by a NiII-aryl complex under long-wave UV (390–395 nm) irradiation in the presence of a soluble amine base without any additional photosensitizer, the reaction enables the etherification of aryl bromides and aryl chlorides as well as sulfonates with a wide range of primary and secondary aliphatic alcohols, affording synthetically important ethers. Intramolecular C?O coupling is also possible. The reaction appears to proceed via a NiI–NiIII catalytic cycle.

Iron-catalyzed olefin hydrogenation at 1 bar H2 with a FeCl3-LiAlH4 catalyst

The scope and mechanism of a practical protocol for the iron-catalyzed hydrogenation of alkenes and alkynes at 1 bar H2 pressure were studied. The catalyst is formed from cheap chemicals (5 mol% FeCl3-LiAlH4, THF). A homogeneous mechanism operates at early stages of the reaction while active nanoparticles form upon ageing of the catalyst solution. This journal is

A general and efficient catalyst for palladium-catalyzed C-O coupling reactions of aryl halides with primary alcohols

An efficient procedure for palladium-catalyzed coupling reactions of (hetero)aryl bromides and chlorides with primary aliphatic alcohols has been developed. Key to the success is the synthesis and exploitation of the novel bulky di-1-adamantyl-substituted bipyrazolylphosphine ligand L6. Reaction of aryl halides including activated, nonactivated, and (hetero)aryl bromides as well as aryl chlorides with primary alcohols gave the corresponding alkyl aryl ethers in high yield. Noteworthy, functionalizations of primary alcohols in the presence of secondary and tertiary alcohols proceed with excellent regioselectivity.