27410-03-3

Basic information

• Product Name: 3-Phenyl-1,4-pentadiin-3-ol
• Synonyms: 3-Phenyl-1,4-pentadiin-3-ol
• CAS NO: 27410-03-3
• Molecular Weight: 156.184
• Mol File: 27410-03-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Phenyl-1,4-pentadiin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyl-1,4-pentadiin-3-ol(27410-03-3)
• EPA Substance Registry System: 3-Phenyl-1,4-pentadiin-3-ol(27410-03-3)

Safety Data

• Hazardous Substances Data: 27410-03-3(Hazardous Substances Data)

Upstream product

• 93-99-2 benzoic acid phenyl ester 
• 74-86-2 acetylene 
• 3623-15-2 phenyl propargyl ketone 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 100-52-7 benzaldehyde 
• 13829-77-1 3-(trimethylsilyl)-1-phenyl-2-propyn-1-one 
• 93-89-0 benzoic acid ethyl ester 
• 99048-51-8 3-phenyl-1-(trimethylsilyl)penta-1,4-diyn-3-ol 
• 1066-26-8 sodium acetylide 

Downstream Products

• 1207551-06-1 2-(1-ethynyl-1-phenyl-prop-2-ynyloxy)-ethanol 
• 78630-00-9 Pt(HC₂COHC₆H₅CCH)(P(C₆H₅)3)2 
• 63428-61-5 1,4-Dihydro-r-4-methoxy-4-phenyl-t-1-(p-tolyl)arsenin 
• 63428-61-5 1,4-Dihydro-r-4-methoxy-4-phenyl-c-1-(p-tolyl)arsenin 
• 63428-62-6 1,4-Dihydro-r-methoxy-t-1,4-diphenylarsenin 
• 63428-62-6 1,4-Dihydro-r-methoxy-c-1,4-diphenylarsenin 
• 20930-03-4 N-Cyclohexyl-carbaminsaeure-<3-phenyl-3-aethinyl-propin-(1)-yl-(3)>-ester 
• 51110-57-7 3-phenyl-3-methoxypenta-1,4-diyne 
• 27390-88-1 3-phenylpent-2-en-4-ynal 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF PI3-KINASE SIGNALING

Provided are certain 1,2,3-triazole and 1,2,3-triazole dimer analogs of DM-PIT-1 which are second-generation selective non-phosphoinositide small molecule inhibitors of phosphatidylinositol-3,4,5-trisphosphate (PIP3), including 1,2,3-triazoles represented by formula (I) where: Ar represents aryl or heteroaryl; X represents O or S; each of Ra, Rb, Rc, and Rd independently represents hydrogen, halogen, C1-C10alkyl, -OH, -CF3, aryl, amino, or nitro; and Ar is optionally substituted with one or more substituents independently selected from the group consisting of halogen, C1-Cioalkyl, -OH, -CF3, amino, and nitro. Also provided are pharmaceutical compositions comprising compounds of the invention and a pharmaceutical carrier. Also provided are methods of inhibiting PIP3-mediated signaling in a cell and treating cancer using compounds of the invention.

SYNTHESIS OF 3-METHYL- AND 3-ARYLPENTENYNYL ALCOHOLS, ETHERS, AND ALDEHYDES

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