2749-68-0

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, 1,3-Dioxepane, 2-phenylhas 11 carbon atoms, 14 hydrogen atoms, and 2 oxygen atoms.

Explanation

The compound has a six-membered ring structure with oxygen atoms at positions 1 and 3, and a phenyl group (C6H5) attached to position 2.

Explanation

The ether functional group is formed by the oxygen atoms in the six-membered ring, while the phenyl group provides an aromatic ring structure.

Explanation

Due to its unique structure and reactivity, 1,3-Dioxepane, 2-phenylis used as a starting material or intermediate in the synthesis of various compounds in the pharmaceutical, agrochemical, and fragrance industries.

Explanation

The compound serves as a versatile building block in organic chemistry, allowing chemists to create more complex molecules by attaching additional functional groups or modifying its structure.

Explanation

The unique structure and reactivity of 1,3-Dioxepane, 2-phenylmake it a promising candidate for the development of new materials and polymers with specific properties and applications.

Explanation

Due to its ether and aromatic ring structures, 1,3-Dioxepane, 2-phenylcan participate in a range of chemical reactions, such as electrophilic aromatic substitution, nucleophilic addition, and oxidation reactions.

Explanation

As an organic compound, 1,3-Dioxepane, 2-phenylis expected to be soluble in common organic solvents like dichloromethane, ethyl acetate, and acetone.

Explanation

The compound is relatively stable under normal conditions, such as room temperature and atmospheric pressure, but may undergo degradation or reactions under extreme conditions or in the presence of strong reagents.

Explanation

As with any chemical compound, 1,3-Dioxepane, 2-phenylshould be handled with care, following proper safety protocols and precautions to minimize potential hazards, such as flammability, toxicity, or reactivity with other substances.

Structure

Cyclic ether with a six-membered ring and a phenyl group

Functional Groups

Ether and aromatic ring

Applications

Synthesis of pharmaceuticals, agrochemicals, and fragrances

Use in Organic Chemistry

Building block for complex molecules

Potential Applications

Development of new materials and polymers

Reactivity

Can undergo various chemical reactions

Solubility

Generally soluble in organic solvents

Stability

Relatively stable under normal conditions

Safety

Handle with care due to potential hazards

Upstream product

• 110-63-4 Butane-1,4-diol 
• 100-52-7 benzaldehyde 
• 2568-24-3 2-phenyl-4,7-dihydro-1,3-dioxepine 
• 56318-28-6 (bis(allyloxy)methyl)benzene 
• 1125-88-8 benzaldehyde dimethyl acetal 

Downstream Products

• 32651-37-9 4-benzoyloxybutan-1-ol 
• 22927-31-7 4-oxobutyl benzoate 
• 36978-34-4 benzoicacid 4-bromo-butyl ester 
• 4541-14-4 4-benzyloxy-butan-1-ol 
• 389852-59-9 diethyl [1,1-2H₂]-4-benzyloxybutyl-N-t-butoxycarbonylaminomalonate 
• 389852-62-4 N-(4-benzyloxy-[1,1-2H₂]butyl)phthalimide 
• 389852-58-8 [1,1-2H₂]-4-benzyloxy-1-bromobutane 
• 31600-62-1 [1,1-2H₂]-4-benzyloxy-butan-1-ol 
• 10385-30-5 4-(benzyloxy)butanoic acid 
• 31600-42-7 methyl 4-(benzyloxy)butanoate 
• 101-81-5 Diphenylmethane 

Relevant academic research and scientific papers

Lewis Acid-Catalyzed Vinyl Acetal Rearrangement of 4,5-Dihydro-1,3-dioxepines: Stereoselective Synthesis of cis- And trans-2,3-Disubstituted Tetrahydrofurans

Lewis acid-catalyzed rearrangements of 4,5-dihydro-1,3-dioxepines have been investigated. Rearrangement of vinyl acetals under a variety of conditions resulted in cis- and trans-2,3-disubstituted tetrahydrofuran derivatives in a highly stereoselective man

Phosphotungstic Acid Supported on Magnetic Mesoporous Tantalum Pentoxide Microspheres: Efficient Heterogeneous Catalysts for Acetalization of Benzaldehyde with Ethylene Glycol

Abstract: In this study, magnetically-recoverable core–shell catalysts with different amount of H3PW12O40 loading [Fe3O4@C@mTa2O5-NH2-PW12 (w%)] were prepared by the application of phosphotungstic acid supported on amino group functionalized magnetic core–shell mesoporous tantalum pentoxide microspheres. The prepared samples were characterized by FT-IR, N2-adsorption–desorption isotherms, TEM, SEM, Pyridine-IR analysis, XRD and magnetism. Fe3O4@C@mTa2O5-NH2-PW12 samples present both Br?nsted and Lewis acidity, large BET surface area and high magnetization. The catalytic activity was evaluated by the acetalization of different aldehydes with diols, and the results show that Fe3O4@C@mTa2O5-NH2-PW12 (14.47%) catalyst exhibits the highest catalytic activity for acetalization of aldehydes with glycols with 94.5% conversion of benzaldehyde and 99% selectivity to benzaldehyde glycol acetal at 80?°C. The catalytic activity of the catalyst for acetalization is related to its total acidity and Br?nsted–Lewis acid synergy. The catalyst Fe3O4@C@mTa2O5-NH2-PW12 can be easily recovered and reused for at least 5 times without obvious decrease of catalytic activity.

Phosphorus promoted SO42-/TiO2 solid acid catalyst for acetalization reaction

A novel phosphorus modifed SO42-/TiO2 catalyst was synthesized by a facile coprecipitation method, followed by calcination. The catalytic performance of this novel solid acid was evaluated by acetalization. The results showed that the phosphorus was very effcient to enhance the catalytic activity of SO42-/TiO2. The solid acid owned high activity for the acetalization with the yields over 90%. Moreover, the solid acid could be reused for six times without loss of initial catalytic activities.

Synthesis of sulfonic acid-functionalized MIL-101 for acetalization of aldehydes with diols

A metal-organic framework (MOF) MIL-101 bearing sulfonic acid groups (SO3H-MIL-101), was prepared through one-pot hydrothermal synthesis strategy. This MOF was systemically characterized via XRD, N2 adsorption, acid-base titration, XPS, FT-IR techniques, and elemental analysis, and then used as a heterogeneous catalyst for liquid-phase acetalizations of various aldehydes with diols. The obtained SO3H-MIL-101 shows high catalytic activity in the acetalizations due to the high utilization efficiency of its functionalized acid sites. Additionally, this catalyst can be easily recovered and reused five times in succession without significant loss of catalytic activity.

Preparation of a novel solid acid catalyst with Lewis and Bronsted acid sites and its application in acetalization

A novel melamine-formaldehyde resin (MFR) supported solid acid with Lewis and Bronsted acid sites was synthesized through the immobilization of acidic ionic liquid and cuprous ion on MFR. The scanning electron microscopy (SEM) characterization showed that addition of PEG-2000 in the synthesis of MFR could promote the formation of regular particles with diameters around 3.7 μm. The XRD pattern demonstrated that some cuprous ions were aggregated. The catalytic performance of this acid catalyst was evaluated by acetalization. The results showed that the catalytic activity of MFR with Bronsted acid could be improved by addition of Lewis acid. The solid acid was very efficient for the acetalization of carbonyl compounds and diols with moderate to excellent yields and there was no loss of catalytic activity even after being recycled for 6 runs. TUeBITAK.

Synthesis of a novel melamine-formaldehyde resin-supported ionic liquid with Bronsted acid sites and its catalytic activities

Bronsted acidic ionic liquid immobilized on a melamine-formaldehyde resin (AIL-MFR) was synthesized through the reaction of melamine-formaldehyde resin (MFR) with 1,4-butanesulfonate. Using PEG-2000 as the additive, the MFR can be prepared in regular microspheres with an average diameter of 3.97 μm and surface area of 9.09 m2 g-1. The AIL-MFR had high acidity of 2.93 mmol g-1, mainly from the sulfonic groups. The catalysis results showed that the AIL-MFR had high activity and stability for acetalization with excellent conversions and yields for most substrates. Furthermore, immobilization of the acidic ionic liquid on the MFR made the recycling of the catalyst convenient.

Sulfonic groups functionalized preoxidated polyacrylonitrile nanofibers and its catalytic applications

A SO3H-bearing nanofiber mat was synthesized and investigated as a novel heterogeneous acid catalyst. Preoxidated polyacrylonitrile nanofiber mat was prepared via electrospinning and heat treatment, and then reacted with chlorosulfuric acid to introduce the sulfonic groups. The nanofiber mat owned high acidity of 2.99 mmol/g. The preoxidation and sulfonation were examined by FT-IR spectroscopy, elemental analysis and X-ray diffraction spectroscopy (XRD). The fiber morphologies were characterized by scanning electron microscopy (SEM). The catalytic activities and reuse of the prepared nanofiber mat solid acid catalyst have been evaluated for the acetalization and esterification. The regular fiber mat structure could significantly facilitate the recovery and reuse of the catalyst. The excellent catalytic performance and easy recycling made the novel fiber mat solid acid hold great potential for the green chemical processes.

Synthesis of a novel multi-SO3H functionalized ionic liquid and its catalytic activities

A novel multi-SO3H functionalized ionic liquid is synthesized and a detailed account of its cata- lytic activities in acetalization and acetylation is given. The results showed that the ionic liquid is very efficient in the conventional acid-catalyzed reactions with good to excellent yields within a short reaction time. Oper- ational simplicity, small amounts required, low cost of the catalyst, high yields, scalability and reusability are the key features of this methodology, which indicates the high potentialities of the novel ionic liquid to be used in environmentally friendly processes. Pleiades Publishing, Ltd., 2012.

Acetalization of carbonyl compounds catalyzed by acidic ionic liquid immobilized on silica gel

Imidazolium-silica heterogeneous catalyst (SG-[(CH2) 3SO3H-HIM]HSO4) was prepared by immobilization of acidic ionic liquid 1-(propyl-3-sulfonate) imidazolium hydrosulfate ([(CH2)3SO3H-HIM]HSO4) on silica-gel using tetraethoxysilane (TEOS) as silica source in this study. The properties of the samples were characterized by FT-IR, SEM and TG/DSC. The results suggested that [(CH2)3SO3H-HIM]HSO4 had been successfully immobilized on the surface of silica-gel and the immobilized ionic liquid catalyst SG-[(CH2)3SO 3H-HIM]HSO4 had good thermal stability. The original smooth surface of silica-gel was covered with [(CH2) 3SO3H-HIM]HSO4 and a rough surface of SG-[(CH2)3SO3H-HIM]HSO4 was formed, but the size of particles had no obvious change. Moreover, SG-[(CH 2)3SO3H-HIM]HSO4 exhibited high catalytic activity for a series of acetalization and could be recovered easily. After reused for 10 times in the synthesis of benzaldehyde ethanediol acetal, the catalyst could still give satisfactory catalytic activity.

Highly stereoselective synthesis of 2,5-disubstituted (E, E)-penta-2,4-dienals

A condensation of α,β-unsaturated aldehydes with O-protected 4-hydroxybutanal N-(tert-butyl)-imine has been exemplified for the first time using (E)-cinnamic and (E)-4-methoxycinnamic aldehydes. (E,E)-2,5-Disubstituted penta-2,4-dienals, which are key intermediates in the synthesis of strobilurins A and X, were prepared in good yields and close to 100% stereoselectivity.