2755-70-6Relevant academic research and scientific papers
Synthesis and characterization of 2-phenylpyrazoline derivatives and evaluation of their activities against antimicrobial and breast cancer cell line in vitro and in silico studies
Chinnamanayakar, Raja,Ezhilarasi
, p. 1311 - 1320 (2019/06/10)
The new series of 2-phenylpyrazoline derivatives (2a-j) were synthesized and evaluated for their antimicrobial, in silico and in vitro anticancer activity was performed by MTT assay using MDA-MB-231 (human breast adenocarcinoma) cell line. The 2-phenylpyr
SAR studies of differently functionalized 4′-phenylchalcone based compounds as inhibitors of cathepsins B, H and L
Ravish, Indu,Raghav, Neera
, p. 50440 - 50453 (2015/06/25)
Conditions related to the elevated levels of cathepsin B [3.4.22.1], cathepsin H [3.4.22.16] and cathepsin L [3.4.22.15] in various cancerous, rheumatoid arthritis and tissue degenerative disorders motivate the design, synthesis and evaluation of compound
Synthesis and antimicrobial evaluation of some halcones and their derived pyrazoles, pyrazolines, isoxazolines, and 5,6-dihydropyrimidine-2-(1H)-thiones
Abdel-Rahman, Adel A.-H.,Abdel-Megied, Ahmed E.-S.,Hawata, Mohamed A. M.,Kasem, Eman R.,Shabaan, Mohamed T.
, p. 889 - 897 (2008/02/11)
Chalcones were synthesized by a base catalyzed Claisen-Schmidt condensation reaction. Bromination of chalcones afforded the dibromo derivatives. Monobromo derivatives could be obtained by treating the corresponding dibromochalcones with dry benzene in the
