276702-53-5 Usage
Description
2,6-dichloro-3-nitrobenzene-1-sulfonyl chloride, also known as 3-nitro-2,6-dichlorobenzenesulfonyl chloride, is a sulfonyl chloride derivative of nitrochlorobenzene with the chemical formula C6H3Cl2NO4S. It is a reactive and highly versatile building block in organic synthesis, often used in the production of dyes, pigments, and other fine chemicals.
Uses
Used in Pharmaceutical Industry:
2,6-dichloro-3-nitrobenzene-1-sulfonyl chloride is used as a key intermediate in the synthesis of sulfonamide and sulfonate derivatives, which are important for the development of pharmaceuticals with various therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,6-dichloro-3-nitrobenzene-1-sulfonyl chloride is used as a building block for the production of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye and Pigment Industry:
2,6-dichloro-3-nitrobenzene-1-sulfonyl chloride is utilized as a reactive intermediate in the synthesis of dyes and pigments, enabling the creation of a wide range of colorants for various applications.
It is important to handle 2,6-dichloro-3-nitrobenzene-1-sulfonyl chloride with caution due to its hazardous nature and potential to cause harmful effects if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 276702-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,6,7,0 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 276702-53:
(8*2)+(7*7)+(6*6)+(5*7)+(4*0)+(3*2)+(2*5)+(1*3)=155
155 % 10 = 5
So 276702-53-5 is a valid CAS Registry Number.
276702-53-5Relevant articles and documents
Comparison of N,N′-diarylsquaramides and N,N′-diarylureas as antagonists of the CXCR2 chemokine receptor
McCleland, Brent W.,Davis, Roderick S.,Palovich, Michael R.,Widdowson, Katherine L.,Werner, Michelle L.,Burman, Miriam,Foley, James J.,Schmidt, Dulcie B.,Sarau, Henry M.,Rogers, Martin,Salyers, Kevin L.,Gorycki, Peter D.,Roethke, Theresa J.,Stelman, Gary J.,Azzarano, Leonard M.,Ward, Keith W.,Busch-Petersen, Jakob
, p. 1713 - 1717 (2007/10/03)
N,N′-diarylsquaramides were prepared and evaluated as antagonists of CXCR2. The compounds were found to be potent and selective antagonists of CXCR2. Significant differences in SAR was observed relative to the previously described N,N′-diarylurea series. As was the case in the N,N′-diarylurea series, placing sulfonamide substituent adjacent to the acidic phenol significantly reduced the clearance in rat pharmacokinetic studies.
Il-8 receptor anatagonists
-
, (2008/06/13)
This invention relates to novel compounds of Formula (I), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
Hydroxy diphenyl urea sulfonamides as IL-8 receptor antagonists
-
, (2008/06/13)
Novell IL-8 compounds and methods of using them are provided.
