27695-70-1

Basic information

• Product Name: (Methoxycarbonylmethylsulfanyl-phenyl-methylsulfanyl)-acetic acid methyl ester
• Synonyms: (Methoxycarbonylmethylsulfanyl-phenyl-methylsulfanyl)-acetic acid methyl ester
• CAS NO: 27695-70-1
• Molecular Weight: 300.4
• Mol File: 27695-70-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Methoxycarbonylmethylsulfanyl-phenyl-methylsulfanyl)-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Methoxycarbonylmethylsulfanyl-phenyl-methylsulfanyl)-acetic acid methyl ester(27695-70-1)
• EPA Substance Registry System: (Methoxycarbonylmethylsulfanyl-phenyl-methylsulfanyl)-acetic acid methyl ester(27695-70-1)

Safety Data

• Hazardous Substances Data: 27695-70-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 2365-48-2 Methyl thioglycolate 
• 186581-53-3 diazomethane 
• 4265-49-0 α,α'-(benzylidenedithio)diacetic acid 

Downstream Products

• 505-73-7 disulfanediyldiacetic acid 
• 144-62-7 oxalic acid 
• 100-52-7 benzaldehyde 
• 10220-27-6 2-phenyl-1,3-thiazolidin-4-one 
• 1402942-10-2 C₁₃H₁₅NO₂S 
• 1402942-56-6 2-phenyl-1,3-thiazolidin-4-one 
• 80353-44-2 2-(Carbamoylmethylsulfanyl-phenyl-methylsulfanyl)-acetamide 

Relevant articles and documents

Catalytic, enantioselective N-acylation of lactams and thiolactams using amidine-based catalysts

In contrast to alcohols and amines, racemic lactams and thiolactams cannot be resolved directly via enzymatic acylation or classical resolution. Asymmetric N-acylation promoted by amidine-based catalysts, particularly Cl-PIQ 2 and BTM 3, provides a convenient method for the kinetic resolution of these valuable compounds and often achieves excellent levels of enantioselectivity in this process. Density functional theory calculations indicate that the reaction occurs via N-acylation of the lactim tautomer and that cation-π interactions play a key role in the chiral recognition of lactam substrates.