27696-41-9

Basic information

• Product Name: HYPOLAETIN
• Synonyms: HYPOLAETIN;3',4',5,7,8-Pentahydroxyflavone;Hypoletin
• CAS NO: 27696-41-9
• Molecular Formula: C₁₅H₁₀O₇
• Molecular Weight: 302.2357
• Mol File: 27696-41-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 0.300 °C (approx)
• Boiling Point: 653.3°Cat760mmHg
• Flash Point: 252.3°C
• Appearance: /
• Density: 1.763g/cm³
• Vapor Pressure: 1.14E-17mmHg at 25°C
• Refractive Index: 1.804
• PKA: 6.65±0.40(Predicted)
• CAS DataBase Reference: HYPOLAETIN(CAS DataBase Reference)
• NIST Chemistry Reference: HYPOLAETIN(27696-41-9)
• EPA Substance Registry System: HYPOLAETIN(27696-41-9)

Safety Data

• Hazardous Substances Data: 27696-41-9(Hazardous Substances Data)

Usage

Definition

ChEBI: A pentahydroxyflavone that consists of luteolin substituted by an additional hydroxy group at position 8.

InChI:InChI=1/C15H10O7/c16-7-2-1-6(3-8(7)17)12-5-10(19)13-9(18)4-11(20)14(21)15(13)22-12/h1-5,16-18,20-21H

Upstream product

• 491-70-3 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on 
• 17290-70-9 isosinensetin 
• 71847-58-0 5,8-dihydroxy-7-methoxy-2-(3,4-dimethoxyphenyl)-4-benzopyrone 
• 32455-43-9 hypolaetin 7-O-β-D-glucopyranoside 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 91856-18-7 2'-hydroxy-3,4,3',4',6'-pentamethoxychalcone 
• 89456-24-6 4-Benzyloxy-3-methoxy-benzoic acid 2-acetyl-6-benzyloxy-3,5-dimethoxy-phenyl ester 
• 89456-17-7 1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(4-benzyloxy-3-methoxy-phenyl)-propane-1,3-dione 
• 89456-31-5 8-Benzyloxy-2-(4-benzyloxy-3-methoxy-phenyl)-5,7-dimethoxy-chromen-4-one 
• 89456-13-3 2,3-bis(benzyloxy)-4,6-dimethoxyacetophenone 
• 54299-57-9 3-benzyloxy-2-hydroxy-4,6-dimethoxyacetophenone 
• 21919-66-4 2,30dihydroxy-4,6-dimethoxyacetophenone 
• 1486-52-8 3-methoxy-4-benzyloxybenzoyl chloride 
• 89456-37-1 8-Hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-5,7-dimethoxy-chromen-4-one 

Downstream Products

• 89473-36-9 5,7,8-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one 
• 18003-33-3 3',4',5,6,7-pentahydroxyflavone 
• 17290-70-9 isosinensetin 
• 137231-85-7 Scutellaprostin C 

Relevant articles and documents

Flavone Glucosides from the Aerial Part of Scutellaria comosa

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Preparation of Synthetic and Natural Derivatives of Flavonoids Using Suzuki–Miyaura Cross-Coupling Reaction

Herein, we report the use of the Suzuki–Miyaura cross-coupling reaction for the preparation of a library of synthetic derivatives of flavonoids for biological activity assays. We have investigated the reactivity of halogenated flavonoids with aryl boronates and with boronyl flavonoids. This reaction was used to prepare new synthetic derivatives of flavonoids substituted at C-8 with aryl, heteroaryl, alkyl, and boronate substituents. The formation of flavonoid boronate enabled a cross-coupling reaction with halogenated flavones yielding biflavonoids connected at C-8. This method was used for the preparation of natural compounds including C-8 prenylated compounds, such as sinoflavonoid NB. Flavonoid boronates were used for the preparation of rare C-8 hy-droxyflavonoids (natural flavonoids gossypetin and hypolaetin). A series of previously unknown derivatives of quercetin and luteolin were prepared and fully characterized.

Studies on nepalese crude drugs. XIV. New flavonoids from the root of Scutellaria prostrata Jacq. ex Benth.

Six flavonoids, named scutellaprostins A, B, C, D, E and F, were isolated from the root of Scutellaria prostrata Jacq. ex Benth. (Labiatae). Their structures were established to be (2R*,3R*)-6-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-hydroxymethyl-9- pheny