278168-49-3Relevant articles and documents
Novel oligonucleotide analogues containing a morpholinoamidine unit
Pérez-Rentero, Sonia,Alguacil, Javier,Robles, Jordi
scheme or table, p. 1171 - 1179 (2009/04/11)
Morpholinoamidines were devised as new cationic units in oligonucleotides, by combining morpholino-nucleosides (to simplify the nomenclature, we will use the term morpholino-nucleosides to refer to nucleoside analogues in which the ribose ring was transfo
Deoxynucleic guanidine: Synthesis and incorporation of purine nucleosides into positively charged DNG oligonucleotides
Challa, Hemavathi,Bruice, Thomas C.
, p. 1475 - 1481 (2007/10/03)
The synthesis of purine nucleosides capable of making the guanidinium linkage is described for the first time starting from the corresponding 2′-deoxynucleosides. The positively charged mixed base DNG oligomer containing guanine was synthesized on solid-p
Solid-phase synthesis of oligomeric deoxynucleic-thiourea (DNT) and deoxynucleic S-methylthiourea (DNmt): A neutral/polycationic analogue of DNA
Arya, Dev P.,Bruice, Thomas C.
, p. 691 - 693 (2007/10/03)
A solid-phase synthesis for oligomeric DNmt is reported. Synthesis proceeds in 3'-5' direction and involves coupling of a protected 3'-isothiocyanate with the corresponding 5'-amine of the growing oligo chain. The difference in oligomeric thiourea/S-methy