27852-91-1

Basic information

• Product Name: Benzenemethanol, 4-chloro-a-(1-nitroethyl)-
• CAS NO: 27852-91-1
• Molecular Formula: C9H10ClNO3
• Molecular Weight: 215.636
• Mol File: 27852-91-1.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-chloro-a-(1-nitroethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-chloro-a-(1-nitroethyl)-(27852-91-1)
• EPA Substance Registry System: Benzenemethanol, 4-chloro-a-(1-nitroethyl)-(27852-91-1)

Safety Data

• Hazardous Substances Data: 27852-91-1(Hazardous Substances Data)

Upstream product

• 79-24-3 Nitroethane 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 3859-51-6 1-(4-chloro-phenyl)-1-(4-fluoro-phenyl)-2-nitro-propane 
• 64777-59-9 optically inactive 1-(4-bromo-phenyl)-1-(4-chloro-phenyl)-2-nitro-propane 
• 117-27-1 (+/-)-1,1-bis-(4-chloro-phenyl)-2-nitro-propane 
• 6285-05-8 4'-chloropropiophenone 
• 23933-83-7 2-amino-1-(4-chlorophenyl)propan-1-ol 
• 859051-13-1 (+/-)-1-(4-bromo-phenyl)-1-(4-chloro-phenyl)-2-aci-nitro-propane 
• 857236-76-1 1,1-bis-(4-chloro-phenyl)-2-aci-nitro-propane 
• 1163136-86-4 1-chloro-4-(2-nitro-1(Z)-propenyl)benzene 
• 158584-54-4 Acetic acid 1-(4-chloro-phenyl)-2-nitro-propyl ester 
• 74261-45-3 1-(4-chlorophenyl)-2-nitro-1-propanone 
• 37629-52-0 (E)-1-(4-chlorophenyl)-2-nitropropene 

Relevant articles and documents

Copper complexes of 1,4-diazabutadiene ligands: Tuning of metal oxidation state and, application in catalytic C-C and C-N bond formation

Reaction of 1,4-diazabutadiene (p-RC6H4N = C(H)(H)C = NC6H4R-p; R = OCH3, CH3, H and Cl; abbreviated as L-R) with CuCl2·2H2O in methanol at ambient temperature (25 °C) affords a group of doubly chloro-bridged dicopper complexes of type [{CuI(L-R)Cl}2], designated as 1-R. Similar reaction carried out in acetonitrile furnishes a family of doubly chloro-bridged dicopper complexes of type [{CuII(L-R)Cl2}2], designated as 2-R. Molecular structures of 1-OCH3 and 2-OCH3 have been determined by X-ray crystallography. While copper(I) is having a nearly tetrahedral N2Cl2 coordination sphere in 1-OCH3, the N2Cl3 coordination sphere around copper(II) is distorted square pyramidal in nature in 2-OCH3. Isolated 2-R complexes, on dissolution in methanol, are found to undergo facile reduction of the metal center to generate the corresponding 1-R complexes. The 1-R and 2-R complexes show intense absorptions in the visible and ultraviolet regions. Cyclic voltammetry on the 1-R and 2-R complexes shows both metal-centered and ligand centered redox responses. The 1-R complexes are found to efficiently catalyze C-N cross-coupling reactions between arylboronic acids and aryl amines; while the 2-R complexes display notable catalytic efficiency for nitroaldol reactions.

Synthesis, Characterization and Catalytic Activity of Magnetic KI@Fe3O4 Nanoparticles for Henry Reaction Under Solvent Free Conditions

Abstract: In this paper, we, for the first time reported the synthesis of KI loaded Fe3O4 nanoparticles (KI@Fe3O4 NPs) and investigated its applications in the synthesis of β-nitroalcohol via Henry reaction at room temperature under solvent-free conditions. The synthesized KI@Fe3O4 nanoparticle was characterized by SEM, HRTEM, XRD, XPS, EDX, VSM and FT-IR spectroscopy techniques. The XRD peaks at 2θ = 21.9, 25.65, 33.54, 36.35, 40.97, 42.81, 44.79, 54.43, 57.37, 58.83 and 63.13° corresponds to the formation of crystalline KI@Fe3O4 NPs. The activity of the catalyst by varying the amount of KI loading on Fe3O4 NPs was also investigated. Mild reaction conditions, good yield, short reaction time, solvent-free conditions, easy recoverability and recyclability of the nanocatalysts are the major advantages of our method. Graphical Abstract: [Figure not available: see fulltext.].

Microwave-assisted synthesis of urea-containing zirconium metal-organic frameworks for heterogeneous catalysis of Henry reactions

Here we report the facile preparation of a urea-containing UiO-68 isoreticular zirconium metal-organic framework (MOF) with mixed dicarboxylate struts by utilizing a microwave-assisted heating method. It can work as an efficient hydrogen-bond-donating heterogeneous catalyst for Henry reactions of benzaldehydes and nitroalkanes. This mixed strut MOF exhibits improved catalytic activity compared to the pure urea-functionalized linker based analogue.