278806-95-4Relevant academic research and scientific papers
9-Amino acridines undergo reversible amine exchange reactions in water: Implications on their mechanism of action in vivo
Paul, Alexis,Ladame, Sylvain
supporting information; experimental part, p. 4894 - 4897 (2010/01/06)
9-Amino substituted acridities undergo a reversible amine exchange reaction In water under near-physiological conditions via an unstable hemiaminal intermediate. This thermodynamically controlled reaction may have Implications In understanding the mode of
Solid-phase synthesis of acridine-peptide conjugates and their analysis by tandem mass spectrometry
Carlson, Coby B.,Beal, Peter A.
, p. 1465 - 1468 (2007/10/03)
(Matrix presented) A novel and high-yielding synthesis of 9-anilinoacridine-4-carboxylic acid is reported. This acid has been used in the solid-phase synthesis of a small combinatorial library of acridine-peptide conjugates. Tandem mass spectrometry (ES-M
