27888-23-9Relevant academic research and scientific papers
Synthesis and biological evaluation of bifendate derivatives bearing acrylamide moiety as novel antioxidant agents
Gu, Xiaoke,Jiang, Yanfei,Chen, Jing,Zhang, Yinpeng,Guan, Mingyu,Li, Xin,Zhou, Qingqing,Lu, Qian,Qiu, Jingying,Yin, Xiaoxing
, p. 59 - 69 (2018/11/21)
Oxidative stress plays a significant role in the pathogenesis of various human diseases. In this study, a series of bifendate derivatives bearing acrylamide moiety were synthesized and evaluated as anti-oxidant agents. Biological evaluation indicated that
Synthesis and transformations of derivatives and analogs of α-cyanocinnamic acid
Ganushchak,Lesyuk,Fedorovich,Obushak,Murarash
, p. 1677 - 1682 (2007/10/03)
A reaction of ethyl α-cyanoacetate with 5-arylfurfurals, furfural, and 4-methoxybenzaldehyde in alkaline water medium gives rise to 3-substituted 2-cyanoacrylic acids in high yield. The reaction of the corresponding acyl chlorides with diethylamine and an
α-Isocyanatoacrylonitriles from alkylidene- or arylidenecyanoacetic acids; synthesis and reactions
Jaafar,Francis,Danion-Bougot,Danion
, p. 56 - 60 (2007/10/02)
The Curtius reaction converts alkylidene- or arylidenecyanoacetic acids to α-isocyanatoacrylonitriles in a stereospecific way. These versatile intermediates allow an easy access to arylacetic acids and various amino acid derivatives, as well as β-lactams or 2-azabutadienes.
