2795-76-8

Basic information

• Product Name: (4-Chlorophenyl)(4-fluorophenyl)Methanol
• Synonyms: (4-Chlorophenyl)(4-fluorophenyl)Methanol
• CAS NO: 2795-76-8
• Molecular Formula: C₁₃H₁₀ClFO
• Molecular Weight: 236.6693032
• Mol File: 2795-76-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (4-Chlorophenyl)(4-fluorophenyl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Chlorophenyl)(4-fluorophenyl)Methanol(2795-76-8)
• EPA Substance Registry System: (4-Chlorophenyl)(4-fluorophenyl)Methanol(2795-76-8)

Safety Data

• Hazardous Substances Data: 2795-76-8(Hazardous Substances Data)

Usage

General Description

The chemical (4-Chlorophenyl)(4-fluorophenyl)Methanol, also known as 4-(4-chlorophenyl)-4-(4-fluorophenyl)butan-1-ol, is an organic compound consisting of a mixture of chlorophenyl and fluorophenyl groups attached to a methanol molecule. (4-Chlorophenyl)(4-fluorophenyl)Methanol is utilized in pharmaceutical research as a potential intermediate in the synthesis of various medications. It is also used as a building block in the production of organic compounds and is studied for its potential pharmacological properties. Additionally, it is important to handle this compound with care due to its potential risks and hazards and, as with all chemicals, it should be used according to safety guidelines and procedures.

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 352-13-6 4-flourophenylmagnesium bromide 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 1765-93-1 4-fluoroboronic acid 
• 448-59-9 tris(4-fluorophenyl)boroxine 
• 108-90-7 chlorobenzene 
• 403-43-0 4-fluorobenzoyl chloride 
• 459-57-4 4-fluorobenzaldehyde 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 2069-48-9 4-chloro-4'-fluoro-benzophenone 

Downstream Products

• 76778-35-3 1-chloro-4-<(2-chloroethoxy)(4-fluorophenyl)methyl>benzene 
• 1202767-54-1 3-[(4-Chlorophenyl)(4-fluorophenyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indole 
• 64583-42-2 1-(bromo(4-chlorophenyl)methyl)-4-fluorobenzene 
• 64583-39-7 (p-chlorophenyl)-(p-fluorophenyl)methyl chloride 
• 3801-53-4 (4-chlorophenyl)-4-fluorophenylmethane 

Relevant articles and documents

[Ir(COD)Cl]2/tris(2,4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes

[Ir(COD)Cl]2/tris(2,4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes were described. The Ir(I) catalyst, generated from [Ir(COD)Cl]2 and tris(2,4-di-t-butylphenyl)phosphite, was an efficient catalyst system for the addition reactions of a variety of arylboronic acids with aromatic and aliphatic aldehydes. The easy availability of the catalyst and good yields make these reactions potentially useful in organic synthesis.

CuCl/bipyridine-catalyzed addition reactions of arylboroxines with aldehydes, α,β-unsaturated ketones, and N-tosyl aldimines

CuCl/bipyridine-catalyzed addition reactions of arylboroxines with aldehydes and α,β-unsaturated ketones at elevated temperatures were described. By using the microwave energy, CuCl/bipyridine-catalyzed addition reactions of arylboroxines with aldimines were also realized.

Carbinol derivatives via rhodium-catalyzed addition of potassium trifluoro(organo)borates to aldehydes

Reaction of potassium aryltrifluoroborates with aldehydes, in the presence of a rhodium catalyst, afforded carbinol derivatives in high yields under mild aqueous conditions; this efficient reaction proved to be general, allowing the production of highly hindered diarylmethanols and aliphatic aldehydes were also reactive under these conditions. The Royal Society of Chemistry 2005.