27958-97-0

Usage

Uses

Used in Organic Synthesis:
N-(3-aminobenzyl)-N,N-diethylamine is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions, contributing to the creation of a wide range of compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, N-(3-aminobenzyl)-N,N-diethylamine is utilized as a key intermediate in the synthesis of various drugs, playing a crucial role in the development of new medicinal compounds.
Used in Agrochemical Production:
Similarly, in agrochemicals, N-(3-aminobenzyl)-N,N-diethylamine serves as an essential component in the synthesis of products designed to protect and enhance crop yields, contributing to agricultural productivity.
Used in Corrosion Inhibition:
N-(3-aminobenzyl)-N,N-diethylamine has been studied for its potential as a corrosion inhibitor, used to protect metals from degradation in various industrial applications, thereby extending the lifespan of metal structures and equipment.

InChI:InChI=1/C11H18N2/c1-3-13(4-2)9-10-6-5-7-11(12)8-10/h5-8H,3-4,9,12H2,1-2H3

Upstream product

• 68269-83-0 3-amino-N,N-diethylbenzamide 
• 27958-92-5 diethyl(3-nitrobenzyl)amine 

Downstream Products

• 83196-67-2 7-chloro-N-<3-(diethylamino)methylphenyl>-4-quinolinamine 
• 874513-91-4 diethyl-[3-(2-nitro-anilino)-benzyl]-amine 
• 144128-45-0 7-Chloro-3-(3,4-dichloro-phenyl)-1-[(E)-3-diethylaminomethyl-phenylimino]-10-hydroxy-1,3,4,10-tetrahydro-2H-acridin-9-one 
• 874513-93-6 N-(3-diethylaminomethyl-phenyl)-o-phenylenediamine 
• 1256163-16-2 5-(3-((diethylamino)methyl)phenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde 
• 503183-47-9 4-[(3-diethylaminomethylphenyl)hydrazono]-4H-pyrazole-3,5-diamine 

Relevant academic research and scientific papers

Synthesis and antimalarial activity of new analogues of amodiaquine

In order to determine the real significance of the 4′-phenolic group in the antimalarial activity and/or cytotoxicity of amodiaquine (AQ), analogues for which this functionality was shifted or modified were synthesized. Good in vitro antimalarial activity

PYRIMIDINE UREA DERIVATIVES AS KINASE INHIBITORS

The invention relates to compounds of formula (I) wherein the substituents X1, R1, R2, R3 and R4 have the meaning as set forth and explained in the description of the invention, to processes for the preparation of these compounds, pharmaceutical compositions containing same, the use thereof optionally in combination with one or more other pharmaceutically active compounds for the therapy of a disease which responds to an inhibition of protein kinase activity, and a method for the treatment of such a disease.

Synthesis of potent and selective 2-azepanone inhibitors of human tryptase

The serine protease tryptase has been associated with a broad range of allergic and inflammatory diseases and, in particular, has been implicated as a critical mediator of asthma. The inhibition of tryptase therefore has the potential to be a valuable therapy for asthma. The synthesis, employing solution phase parallel methods, and SAR of a series of novel 2-azepanone tryptase inhibitors are presented. A member of this series, 8t, was identified as a potent inhibitor of human tryptase (IC50=38 nM) with selectivity ≤330-fold versus related serine proteases (trypsin, plasmin, uPA, tPA, APC, alpha-thrombin, and FXa).