280110-78-3

Basic information

• Product Name: 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)PIPERIDINE(MINIMUM90%)
• Synonyms: 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)PIPERIDINE(MINIMUM90%) ;2-Phenyl-5-(piperidin-4-yl)-1,3,4-oxadiazole, [5-(Piperidin-4-yl)-1,3,4-oxadiazol-2-yl]benzene;4-(5-Phenyl-1,3,4-oxadiazol-2-yl)piperidine90+%;2-phenyl-5-(piperidin-4-yl)-1,3,4-oxadiazole
• CAS NO: 280110-78-3
• Molecular Formula: C₁₃H₁₅N₃O
• Molecular Weight: 229.2777
• Mol File: 280110-78-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 89-91°C
• Boiling Point: 391.9°Cat760mmHg
• Flash Point: 190.8°C
• Appearance: /
• Density: 1.139g/cm³
• Vapor Pressure: 2.39E-06mmHg at 25°C
• Refractive Index: 1.548
• PKA: 9.57±0.10(Predicted)
• CAS DataBase Reference: 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)PIPERIDINE(MINIMUM90%)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)PIPERIDINE(MINIMUM90%)(280110-78-3)
• EPA Substance Registry System: 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)PIPERIDINE(MINIMUM90%)(280110-78-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 280110-78-3(Hazardous Substances Data)

Usage

General Description

4-(5-Phenyl-1,3,4-oxadiazol-2-yl)piperidine (minimum 90%) is a chemical compound with a minimum purity of 90%. It belongs to the class of piperidine derivatives and contains a phenyl group and an oxadiazol ring. 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)PIPERIDINE(MINIMUM90%) is often used in pharmaceutical research and drug development due to its potential biological activities. It may have applications in the synthesis of various drugs, including potential psychiatric, neurological, and cardiovascular medications. Its precise properties and applications depend on the specific research or production process for which it is used.

InChI:InChI=1/C13H15N3O/c1-2-4-10(5-3-1)12-15-16-13(17-12)11-6-8-14-9-7-11/h1-5,11,14H,6-9H2

Upstream product

• 1031156-54-3 tert-butyl 4-(2-benzoylhydrazinecarbonyl)piperidine-1-carboxylate 
• 124443-68-1 1-tert-Butyl 4-methyl piperidine-1,4-dicarboxylate 
• 613-94-5 benzoic acid hydrazide 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 280110-70-5 4-(5-phenyl-[1,3,4]oxadiazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester 
• 187834-88-4 tert-butyl 4-(hydrazinecarbonyl)piperidine-1-carboxylate 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 

Downstream Products

• 1419956-62-9 [4-(5-phenyl-[1,3,4]oxadiazol-2-yl)-piperidin-1-yl]-acetic acid 
• 1419951-13-5 C₂₃H₂₆N₆O₄ 

Relevant articles and documents

SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION

The present invention covers aminoquinolone compounds of general formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8 and n are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and/or prophylaxis of diseases, in particular of diacylglycerol kinase alpha regulated disorders, as a sole agent or in combination with other active ingredients.

NOVEL 2-PIPERIDIN-1-YL-ACETAMIDE COMPOUNDS FOR USE AS TANKYRASE INHIBITORS

The present invention provides for compounds of formula (I), wherein R1-R5 and L are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.