28078-91-3Relevant academic research and scientific papers
Na2CO3-promoted thioesterification via N–C bond cleavage of amides to construct thioester derivatives
Tao, Jiasi,Yu, Weijie,Luo, Jin,Wang, Tao,Ge, Wanling,Zhang, Ziwei,Yang, Bingjie,Xiong, Fei
, p. 486 - 492 (2019)
A mild, efficient, and transition-metal-free catalytic strategy is developed to construct thioesters via selective N–C bond cleavage of Boc2-activated primary amides. This strategy is successfully carried out with stoichiometric Na2C
Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water
Nambu, Hisanori,Hata, Kayoko,Matsugi, Masato,Kita, Yasuyuki
, p. 719 - 727 (2007/10/03)
The combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (VA-044) and the surfactant, cetyltrimethyl-ammonium bromide (CTAB), was found to be the most suitable condition for the effective and direct synthesis of useful active thioesters (pentafluorophenyl thioesters) in water. In addition, the direct amidation of aldehydes was achieved by the addition of the amines to the thioesterification reaction mixture in water.
The direct synthesis of thioesters using an intermolecular radical reaction of aldehydes with dipentafluorophenyl disulfide in water
Nambu, Hisanori,Hata, Kayoko,Matsugi, Masato,Kita, Yasuyuki
, p. 1082 - 1083 (2007/10/03)
The combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (VA-044), and surfactant, cetyltrimethylammonium bromide (CTAB), was found to be the most suitable condition for the effective direct synthes
Fluoro-organic sulphur-containing compounds. IV. Haloalkylation reactions of polyfluorinated thiophenols with CHal3R compounds in the presence of AlCl3: Synthesis and some reactions of polyfluorophenylthio derivatives of halomethanes
Petrova,Platonov,Maksimov
, p. 17 - 28 (2007/10/03)
The haloalkylation of polyfluorothiophenols with CHal3R compounds (Hal=Cl, F; R=Cl, H, C6H5, C6F5) in the presence of AlCl3 has been investigated. The reactions of polyfluorothiophenols 4-XC6F4SH (X=F, H, CH3) with CCl4 and AlCl3 lead to dichloromethane derivatives (4-XC6F4S)2CCl2. The reaction of pentafluorothiophenol with CHCl3 in the presence of AlCl3 gave (C6F5S)2CHCl and (C6F5S)3CH (ratio by GLC 8:1). In the reaction of pentafluorothiophenol with ArCX3 (Ar=C6H5, C6F5; X=Cl, F) compounds (C6F5S)2CClAr (Ar=C6H5, C6F5) together with C6F5SCCl2Ar (Ar=C6H5, C6F5) are formed. Peculiarities of these processes are considered. The hydrolysis of (C6F5S)2CCl2 and C6F5SCCl2C6H5 leads to bis(pentafluorophenyl)dithiocarbonate and the S-(pentafluorophenyl) ester of thiobenzoic acid, respectively. Compounds (C6F5S)2CF2 and (C6F5S)2CClF were obtained from (C6F5S)2CCl2 by the action of caesium fluoride. An attempt to produce these compounds through the action of antimony fluorides was unsuccessful. The compounds (C6F5S)2CCl2, (C6F5S)2CClF and (C6F5S)2CF2 are stable to oxidation. The reactions of (C6F5S)2CF2 and (C6F5S)2CClF with CrO3 in acetic acid proceeded only with the formation of mono-sulphoxide. The conversion is low in the former case.
