618-38-2

Usage

Uses

Used in Organic Synthesis:
Benzoyl iodide is used as a reagent for the preparation of aromatic ketones and carboxylic acids, playing a crucial role in advancing various chemical reactions and syntheses.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, benzoyl iodide is employed as a reagent in the synthesis of specific pharmaceutical compounds, contributing to the development of new medications and therapeutic agents.
Used in Radical Reactions:
Benzoyl iodide serves as a source of aromatic radicals in radical reactions, which are essential for certain types of chemical transformations, particularly in the context of organic chemistry.
Safety Considerations:
Due to its high toxicity and corrosive nature, benzoyl iodide should be handled with extreme caution. It is imperative to work in a well-ventilated environment and to use appropriate protective equipment to ensure safety during its use in any application.

InChI:InChI=1/C7H5IO/c8-7(9)6-4-2-1-3-5-6/h1-5H

Upstream product

• 98-88-4 benzoyl chloride 
• 10034-85-2 hydrogen iodide 
• 60-29-7 diethyl ether 
• 7553-56-2 iodine 
• 111772-04-4 trans-Pd(PPh₃)2(Cl)(COPh) 
• 18421-48-2 trans-{PtCOPh(Cl)(PPh₃)2} 
• 65-85-0 benzoic acid 
• 507-02-8 acetyl iodide 

Downstream Products

• 38185-94-3 2-chloro-1,3,3-triphenylprop-2-en-1-one 
• 17436-52-1 benzoyliminotriphenylphosphorane 
• 23094-26-0 2-Benzoyloxy-3-phenyl-4-iod-cyclobuten-⁽²⁾-on 
• 93-55-0 1-phenyl-propan-1-one 
• 98-88-4 benzoyl chloride 
• 93-89-0 benzoic acid ethyl ester 
• 75-03-6 ethyl iodide 
• 591-50-4 iodobenzene 
• 7553-56-2 iodine 
• 94-49-5 1,2-ethanediol, dibenzoate 
• 25537-35-3 2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3]undecan-1-yl benzoate 
• 28078-91-3 (S)-(2,3,4,5,6-pentafluorophenyl) benzenecarbothioate 
• 10101-63-0 lead(II) iodide 
• 103933-66-0 (C₅H₅)Co(CNCOC₆H₅)2 

Relevant academic research and scientific papers

Acyl iodides in organic synthesis: IV. Reaction of acetyl iodide with carboxylic acids

In contrast to acyl chlorides, reactions of acetyl iodide with monocarboxylic acids follow the exchange pattern to give the corresponding acyl iodides and acetic acid. The reaction attracts interest from the preparative viewpoint as a simple and convenient route to acyl iodides. Acetyl iodide reacts with phthalic acid, yielding acetic acid and phthalic anhydride, while the reaction of acetyl iodide with oxalic acid leads to formation of acetic acid, carbon(II) oxide, and molecular iodine.

Benzoyl Halides as Alternative Precursors for the Colloidal Synthesis of Lead-Based Halide Perovskite Nanocrystals

We propose here a new colloidal approach for the synthesis of both all-inorganic and hybrid organic-inorganic lead halide perovskite nanocrystals (NCs). The main limitation of the protocols that are currently in use, such as the hot injection and the liga

A mild method for the replacement of a hydroxyl group by halogen. 1. Scope and chemoselectivity

α-Chloro-, bromo- and iodoenamines, which are readily prepared from the corresponding isobutyramides have been found to be excellent reagents for the transformation of a wide variety of alcohols or carboxylic acids into the corresponding halides. Yields are high and conditions are very mild thus allowing for the presence of sensitive functional groups. The reagents can be easily tuned allowing therefore the selective monohalogenation of polyhydroxylated molecules. The scope and chemoselectivity of the reactions have been studied and reaction mechanisms have been proposed.

Iodide as an activating agent for acid chlorides in acylation reactions

Acid chlorides can be activated using a simple iodide source to undergo nucleophilic attack from a variety of relatively weak nucleophiles. These include Friedel-Crafts acylation of N-methylpyrroles, N-acylation of sulfonamides, and acylation reactions of hindered phenol derivatives. The reaction is believed to proceed through a transient acid iodide intermediate.

Formation of carboxylic acid halides by the reactions of halogens with acetyl-, (phenylacetyl)-, and benzoylchlorobis(triphenylphosphine)platinum(II) and acetyl-, (phenylacetyl)-, and benzoylchloro(triphenylphosphine)palladium(II) complexes

The reactions of the acylmetal complexes trans-[M(PPh3)2Cl(RCO)] where M is Pt or Pd and R is CH3, C6H5CH2, or C6H5 with the halogens (X2) chlorine, bromine