28084-45-9Relevant academic research and scientific papers
Novel dye intermediate, preparation method thereof, novel dyes and preparation methods of novel dyes
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Paragraph 0057; 0064-0065, (2021/05/05)
The invention relates to the field of reactive dyes, and particularly discloses a novel dye intermediate, a preparation method thereof, novel dyes and preparation methods of the novel dyes. The preparation method of the novel dye intermediate comprises the following steps: a, chlorosulfonation; b, reduction; c, condensation; d, hydrogenation reduction; and e, esterification and dilution. The novel dyes provided by the invention have the advantages of higher degree of dyeing, higher fixation rate, better color fastness and more environment-friendly production process.
Pteridinone derivatives as PI3-kinases inhibitors
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Page/Page column 11, (2008/12/07)
New compounds of formula 1 are provided which by virtue of their pharmaceutical activity as PI3-kinase modulators may be used in the therapeutic field for the treatment of inflammatory or allergic diseases. Examples of these include inflammatory and allergic respiratory complaints, inflammatory diseases of the gastro-intestinal tract and motor apparatus, inflammatory and allergic skin diseases, inflammatory eye diseases, diseases of the nasal mucosa, inflammatory or allergic conditions involving autoimmune reactions or inflammations of the kidney.
EFFECT OF STRUCTURE ON THE KINETICS AND MECHANISM OF THE ACID-CATALYZED DECOMPOSITION OF N-ALKYL-N-NITROBENZENESULFONAMIDES
Drozdova, O. A.,Astrat'ev, A. A.,Kuznetsov, L. L.,Selivanov, V. F.
, p. 671 - 675 (2007/10/02)
The decomposition rate of a series of meta- and para-substituted N-alkyl-N-nitrobenzenesufonamides was determined by a spectrophotometric method in aqueous sulfuric acid.It was shown that the decomposition of the compounds takes place both by denitration and by cleavage of the N-S bond with the formation fo primary aliphatic N-nitrosamines.Electron-withdrawing substituents in the aromatic ring shift the process toward denitration.
EFFECT OF STRUCTURE ON THE KINETICS AND MECHANISM OF THE ACID-CATALYZED DECOMPOSITION OF N-NITROBENZENESULFONAMIDES
Drozdova, O. A.,Astrat'ev, A. A.,Kuznetsov, L. L.,Selivanov, V. F.
, p. 2063 - 2067 (2007/10/02)
The decomposition rate of a series of ring-substituted N-nitrobenzenesulfonamides in aqueous sulfuric acid was measure by a spectrophotometric method.Decomposition of the compounds takes place both by the cleavage of the N-S bond to form the corresponding sulfonic acid, nitrous oxide, and water and by denitration.In crease in the electronegativity of the substituent in the aromatic ring promotes the denitration reaction.
