28129-05-7

Usage

Uses

Used in Pharmaceutical Synthesis:
Dipropynylbenzene is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the formation of diverse chemical entities with potential therapeutic applications.
Used in Organic Compound Synthesis:
Dipropynylbenzene serves as a versatile building block in the synthesis of a wide range of organic compounds, including specialty chemicals, dyes, and other industrial products.
Used in Plastics and Rubbers Industry:
Dipropynylbenzene is used as a stabilizer in the production of plastics and rubbers. Its presence helps to prevent the degradation of these materials, thereby enhancing their durability and performance.
However, it is crucial to handle dipropynylbenzene with care due to its flammable nature and potential health hazards. Inhalation or ingestion of Benzene, (1,1-diMethyl-2-propyn-1-yl)- can be harmful, and prolonged exposure may cause irritation to the respiratory system and skin. Therefore, proper safety measures, including the use of personal protective equipment and adherence to safety protocols, should be taken when working with dipropynylbenzene.

Upstream product

• 141946-94-3 2-phenyl-3-butyn-2-yl acetate 
• 673-32-5 1-Phenylprop-1-yne 
• 80-18-2 Methyl benzenesulfonate 
• 3805-10-5 2,2-(dimethyl)-2-phenylacetaldehyde 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 1195-98-8 2-methyl-2-phenylpropionitrile 
• 127-66-2 2-Phenyl-3-butyn-2-ol 
• 6214-32-0 1-bromo-3-methylbuta-1,2-diene 
• 74-83-9 methyl bromide 

Downstream Products

• 154027-52-8 5-methyl-5-phenyl-3-hexyn-1-ol 
• 38634-65-0 1,1-dimethyl-1,3-dihydro-2H-inden-2-one 
• 770-85-4 2-methyl-2-phenylbutan-3-one 
• 17684-33-2 β,β-dimethyl-β-phenylpropionitrile 
• 154027-49-3 Methanesulfonic acid 5-methyl-5-phenyl-hex-3-ynyl ester 

Relevant academic research and scientific papers

Dual Gold Catalysis: Synthesis of Fluorene Derivatives from Diynes

1,5-Diyne systems bearing one terminal and one benzyl- or allyl-substituted alkyne attached to an aromatic backbone were converted in the presence of a gold catalyst. In a dual gold-catalyzed process, gold vinylidenes are formed that selectively undergo formal CH insertion into the C(sp2)–H bond of the offered unsaturated systems. If H atoms are present in the propargylic position, a subsequent isomerization to the aromatic system takes place leading to 9H-fluorene and 11H-benzo[b]fluorene derivatives as final products. In the case of a quaternary carbon in the propargylic position no further aromatization is observed and 10H-benzo[b]fluorene derivatives are obtained in high yield. (Figure presented.).

Biarylphosphonite gold(I) complexes as superior catalysts for oxidative cyclization of propynyl arenes into indan-2-ones

Striking gold: A series of variously functionalized propynyl arenes was smoothly converted into indan-2-ones by a new gold(I)-catalyzed oxidative cyclization process. [LAu]NTf2 (Tf=trifluoromethanesulfonyl) is a superior catalyst both in terms of yield and kinetics for the present transformation. Copyright

REACTIONS OF 3-ALKYL- AND 3,3-DIALKYL-1-BROMOALLENES WITH ORGANOCUPRATES: EFFECTS OF THE NATURE OF THE CUPRATE REAGENT ON THE REGIO- AND STEREOSELECTIVITY

Organocuprates induce 1,3- and direct substitution in 3-alkyl- and 3,3-dialkyl-1-bromo-1,2-dienes leading respectively to either terminal acetylenes or allenic hydrocarbons.The nature of the cuprate exerts a prominent role in determining both the regio- and the stereochemistry of these reactions.

Synthesis of Chiral Alk-1-ynes containing an α-Phenylethyl Group

(R)-4-Phenylpent-1-yne, (R)-(1b), and (S)-5-phenylhex-1-yne, (S)-(1c), have been synthesised from the corresponding chiral alk-1-enes (2) by a stereospecific bromination-dehydrobromination procedure.On the other hand, (R)-3-phenylbut-1-yne, (R)-(1a), has