770-85-4Relevant articles and documents
Rearrangement of Ketones. Part 3. Kinetic Study and Intermediate Complexes in the Reaction of t-Butyl Phenyl Ketone with Aluminium Chloride
Fernandez-Monreal, Maria C.,Ruiz, Maria P.,San-Roman, Julio
, p. 1983 - 1988 (1988)
A kinetic study of the rearrangement of t-butyl phenol ketone to 3-methyl-3-phenylbutan-2-one with aluminium chloride is reported.In addition, a study by (1)H and (13)C n.m.r. of the system t-butyl phenyl ketone-aluminium chloride in benzene shows the con
Lewis Acid Assisted Electrophilic Fluorine-Catalyzed Pinacol Rearrangement of Hydrobenzoin Substrates: One-Pot Synthesis of (±)-Latifine and (±)-Cherylline
Shi, Hui,Du, Chuan,Zhang, Xinhang,Xie, Fukai,Wang, Xiaoyu,Cui, Shanshan,Peng, Xiaoshi,Cheng, Maosheng,Lin, Bin,Liu, Yongxiang
, p. 1312 - 1319 (2018/02/09)
A microwave-irradiated solvent-free pinacol rearrangement of hydrobenzoin substrates catalyzed by a combination of N-fluorobenzenesulfonimide and FeCl3·6H2O was developed. Its selectivity was first investigated by density functional theory (DFT) calculations. Then the functional group tolerance was examined by synthesizing a series of substrates designed based on the insight provided by the DFT calculations. The application of the methodology was demonstrated by the efficient one-pot synthesis of (±)-latifine and (±)-cherylline, both are 4-aryltetrahydroisoquinoline alkaloids isolated from Amaryllidacecae plants.
A gold catalytic pinacone method of rearrangement of
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Paragraph 0067; 0068; 0069; 0070; 0071, (2017/11/22)
The invention provides a method used for catalytic rearrangement of pinacol with gold. A reaction general formula is disclosed in the invention, wherein R1, R2, R3, and R4 may be common alkyl, cycloalkyl, and aromatic rings. A gold catalyst needed by reac